临床危急值与药品不良反应的关联性研究分析

目的:通过监测临床危急值提高药品不良反应(ADR)的上报质量。方法:分析临床药物治疗与出现临床危急值之间的联系,确定可疑的ADR病例。结果:调查中共发现23例疑似ADR报告,占调查期间总上报ADR例数的24.73%;主要ADR表现为血小板减少(13例),其次是尿素升高(5例);给药途径主要为静脉滴注(涉及21例),涉及品种以抗菌药物为主。结论:通过加强对临床危急值的监测,可以提高ADR的报告的质量,减少ADR的漏报率。

Analysis of Correlation Between the Clinical Critical Value and the Adverse Drug Reaction

Objective： To improve the clinical adverse drug reaction （ADR） reporting quality by monitoring the critical value. Methods： The clinical medication and the occurrence of clinical critical value were analyzed to determine the suspected ADR cases. Results： 23 cases of suspected ADR report were found and accounted for 24.73% of the total number of the reported ADR cases during the investigation. The main ADR findings were thrombocytopenia （13 cases）, followed by urea increase （5 cases）. The main administration route was intravenous drip （involving 21 patients）and the main type of drugs was antibacterial drugs. Conelusiun： By strengthening the monitoring of clinical critical value, the quality of ADR reports can be improved and the false negative rate of ADR can be reduced.