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广泛耐药结核分枝杆菌耐药机制及其疾病诊断的研究进展
引用本文:范晓萍,张文宏.广泛耐药结核分枝杆菌耐药机制及其疾病诊断的研究进展[J].微生物与感染,2011,6(2):117-121.
作者姓名:范晓萍  张文宏
作者单位:复旦大学附属华山医院感染科,上海,200040
摘    要:自20世纪90年代以来,全球结核病疫情回升,结核分枝杆菌耐药是其中的一个重要原因.广泛耐药结核病是指在耐多药结核病(即同时对异烟肼和利福平耐药的结核分枝杆菌引起的结核病)的基础上,还对氟喹诺酮类药物和至少3种二线静脉用抗结核药物(卷曲霉素、卡那霉素、阿米卡星)中的1种耐药的结核分枝杆菌引起的结核病.我国是结核病高流行国...

关 键 词:结核分枝杆菌  耐药  流行病学  诊断

Advances in research of extensively drug-resistant tuberculosis
FAN Xiao-Ping,ZHAGN Wen-Hong.Advances in research of extensively drug-resistant tuberculosis[J].Journal of Microbes and Infection,2011,6(2):117-121.
Authors:FAN Xiao-Ping  ZHAGN Wen-Hong
Institution:FAN Xiao-Ping,ZHAGN Wen-Hong Department of Infectious Diseases,Huashan Hospital,Fudan University,Shanghai 200040,China
Abstract:Starting in the 1990s,a global tuberculosis epidemic has risen likely due to the appearance of drug-resistant tuberculosis.First was the worldwide appearance of multidrug-resistant(MDR) tuberculosis followed by extensively drug-resistant(XDR) tuberculosis.MDR tuberculosis is caused by Mycobacterium tuberculosis that is resistant at least to isoniazid and rifampicin.XDR tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin,any kinds of fl...
Keywords:Mycobacterium tuberculosis  Drug resistance  Epidemiology  Diagnosis  
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