除颤时间与心脏性猝死除颤复苏成功率的相关性分析

目的:研究除颤时间与心脏性猝死患者除颤复苏成功率的相关性。方法:选取2015年2月至2017年6月于我院接受除颤复苏治疗的心脏性猝死患者120例为研究对象。分析除颤时间与除颤复苏成功以及心功能舒张早期充盈峰速度(E峰)、左室射血分数(LVEF)、左心室舒张末期内径(LVEDD)以及E/舒张晚期充盈峰速度(A)水平的相关性。结果:电除颤时间2 min患者的复苏成功率为60.00%(21/35),显著高于电除颤时间2~5 min、5~10 min以及10 min患者的34.21%(13/38)、11.11%(3/27)、0.00%(0/20),而电除颤时间2~5 min患者的复苏成功率又显著高于电除颤时间5~10 min患者,差异均有统计学意义(均P0.05)。电除颤时间2 min、2~5 min、5~10 min以及10 min患者的E峰、LVEF、LVEDD以及E/A水平呈逐渐下降趋势,差异均有统计学意义(均P0.05)。Pearson相关性分析结果显示心脏性猝死患者除颤时间与除颤复苏成功率、E峰、LVEF、LVEDD以及E/A均呈负相关关系(r=-0.593,P=0.000;r=-0.476,P=0.001;r=-0.523,P=0.000;r=-0.502,P=0.000;r=-0.469,P=0.001)。结论:除颤时间与心脏性猝死患者除颤复苏成功率呈负相关关系,即除颤时间越早,患者复苏成功率越高。

Correlative Analysis of the Defibrillation Time with Success Rate of Defibrillation Recovery in Patients with Cardiac Sudden Death

ABSTRACT Objective: To study the correlation of defibrillation time with the success rate of defibrillation in patients with cardiac sudden death. Methods: 120 cases of patients with cardiac sudden death were selected from February 2015 to June 2017 in our hospital. The correlation of defibrillation time and cardiac function peak early diastolic filling velocity (peak E), left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD), and E/peak late diastolic filling velocity (A) level were analyzed. Results: The success rate of recovery of patients with defibrillation time < 2 min was 60.00% (21/35), which was significantly higher than that of patients with defibrillation time 2 ~ 5 min, 5 ~ 10 min, and > 10 min34.21% (13/38), 11.11% (3/27), 0.00% (0/20)], and the success rate of recovery of patients with defibrillation time 2~5 min was significantly higher than those of patients with defibrillation time 5~10 min(all P<0.05). The level of E peak, LVEF, LVEDD and E/A of patients with electrode fibrillation time <2 min, 2~5 min, 5~10 min and >10min were gradually decreased with significant differences(all P<0.05). According to Pearson correlative analysis, the success rate of sudden cardiac death in patients with sudden cardiac death was negatively correlated with the recovery success rate, E peak, LVEF, LVEDD and E/A (r = -0.593, P = 0.000; r = -0.476, P = 0.001; r = -0.523, P = 0.000; r = -0.502, P = 0.000; r = -0.469, P = 0.001). Conclusion: The survival rate of patients with cardiac sudden death was negatively correlated with the success rate of defibrillation recovery.