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Local 5-HT signaling bi-directionally regulates the coincidence time window for associative learning
Institution:1. State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China;2. Institute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen 518132, China;3. PKU-IDG/McGovern Institute for Brain Research, Beijing 100871, China;4. Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China;5. National Biomedical Imaging Center, Peking University, Beijing 100871, China;6. Hefei National Laboratory for Physical Sciences at the Microscale, CAS Key Laboratory of Brain Function and Disease, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, Anhui, China;7. Yuanpei College, Peking University, Beijing 100871, China;8. PKU-THU-NIBS Joint Graduate Program, Beijing 100871, China;9. Chinese Institute for Brain Research, Beijing 102206, China;10. School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China;11. Institute of Biophysics, State Key Laboratory of Brain and Cognitive Science, Center for Excellence in Biomacromolecules, Chinese Academy of Sciences, Beijing 100101, China;12. University of Chinese Academy of Sciences, Beijing 100049, China;13. Guangdong Provincial Key Laboratory of Biomedical Optical Imaging Technology & Center for Biomedical Optics and Molecular Imaging & CAS Key Laboratory of Health Informatics, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China;1. MRC Cognition and Brain Sciences Unit, University of Cambridge, 15 Chaucer Road, Cambridge CB2 7EF, UK;2. Department of Experimental Psychology, University of Oxford, Anna Watts Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford OX2 6GG, UK;3. Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford St, Cambridge, MA 02138, USA;1. Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA, USA;2. Electrical and Computer Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA, USA;3. Bioengineering, UCSF – UC Berkeley Joint PhD Program, San Francisco, CA, USA;1. Aix Marseille University, INSERM, INMED (UMR1249), Turing Centre for Living systems, Marseille, France;2. Department of Cell and Developmental Biology, University College London, London, UK;3. Department of Psychology, Durham University, Durham, UK;1. Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA;2. State Key Laboratory of Brain & Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;1. Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, UK;2. Oxford Centre for Human Brain Activity, Wellcome Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK;3. Institute for Brain and Behavior Amsterdam, Department of Experimental and Applied Psychology, Vrije Universiteit Amsterdam, Amsterdam 1081BT, the Netherlands;1. Ernst Struengmann Institute (ESI) for Neuroscience in Cooperation with Max Planck Society, 60528 Frankfurt am Main, Germany;2. Donders Centre for Neuroscience, Department of Neurophysics, Radboud University Nijmegen, 6525 Nijmegen, the Netherlands;3. Department of Psychology, University of Cambridge, CB2 3EB Cambridge, UK;4. Centro de Investigacion en Neuropsicologia y Neurociencias Cognitivas, Facultad de Ciencias de la Salud, Universidad Catolica del Maule, 3480122 Talca, Chile
Abstract:
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  • Keywords:associative learning  coincidence time window  serotonin  synaptic plasticity  olfaction  GRAB sensor
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