布地奈德混悬液雾化吸入治疗小儿急性喉炎的临床观察

目的：观察布地奈德混悬液雾化吸入治疗小儿急性喉炎的临床疗效。方法：选择2010年6月~2012年12月我院收治的急性喉炎患儿67例为研究对象，并将其随机分为对照组和观察组，两组均给予相同的综合性治疗。在此基础上，对照组仅通过静脉给予地塞米松，观察组在地塞米松静脉给药的同时，加用布地奈德混悬液雾化吸入治疗。治疗后，观察和比较两组患儿的症状、体征缓解时间及住院时间。结果：观察组声音嘶哑、犬吠样咳嗽、喉喘呜、吸气性呼吸困难的缓解时间及住院时间均明显短于对照组，观察组雾化吸入布地奈德4h、24h时的临床疗效明显优于对照组，差异有统计学意义（P〈0．05），两组均无不良反应的发生。结论：布地奈德混悬液雾化吸入治疗小儿急性喉炎起效快，病程短，方法简单，不良反应少。

Clinical Observation on the Efficacy of Inhalation Budesonide Suspension in the Treatment of Acute Laryngitis in Children

Objective： To evaluate the clinical efficacy of inhalation budesonide suspension in treating children with acute laryngi- tis. Methods： Sixty-seven cases of acute laryngitis in children were chosen as the research subject from June 2010 to December 2012 in our hospital.They were divided into the observation group and the control group. The two groups were treated with combined therapy of the same.The control group were treated with dexamethasone by intravenous only,the observation group was administered in dexametha- sone by intravenous at the same time,combined with Budesonide Suspension atomization inhalation treatment. And the response duration of different symptoms and physical signs and hospital stays were observed and compared posttreatment. Results： Observation group were significantly shorter than the control group in relieving the hoarseness,barking cough, laryngeal stridor,the inspiratory dyspnea and hospi- tal stays. The clinical efficacy of observation group is superior to the control group inhalation budesonide at 4 h and 24 h .The difference was statistically significant （P〈0.05）. There were no adverse reaction occurred in the two groups. Conclusion： Inhaling budesonide sus- pension in the treatment of acute laryngitis in children shows fast and good effect and the treatment is short and simple with little side ef- fect.