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Modeling Tetrahymena thermophila growth and protease production |
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| Authors: | J De Coninck I Verdier-Denantes F Duyme S Bouquelet V Dumortier |
| Institution: | (1) Institut Supérieur d'Agriculture, Laboratoire de Microbiologie des Fermentations, 41 rue du Port, 59046 Lille Cedex, France, FR;(2) Institut Supérieur d'Agriculture, Laboratoire d'Informatique et de Statistique, 41 rue du Port, 59046 Lille Cedex, France, FR;(3) Université des Sciences et Techniques de Lille, Laboratoire de Chimie Biologique, UMR CNRS 8576, 59655 Villeneuve d'Ascq Cedex, France, FR |
| Abstract: | Oxygen concentrations stimulated growth (maximum number of cells) and protease secretion by Tetrahymena thermophila. Agitation and aeration conditions for growth and protease secretion were optimised by a central composite design. The best optimised combination was a stirrer speed of 338 rpm and an aeration of 1 vvm. Journal of Industrial Microbiology & Biotechnology (2000) 25, 58–61. Received 24 September 1999/ Accepted in revised form 06 March 2000 |
| Keywords: | : agitation aeration Tetrahymena thermophila optimisation protease |
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