| 代谢组学及其在微藻研究中的应用 |
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| 引用本文： | 任丽,张永刚,马睿,周雪飞,张亚雷.代谢组学及其在微藻研究中的应用[J].微生物学通报,2018,45(1):166-172. |
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| 作者姓名： | 任丽 张永刚 马睿 周雪飞 张亚雷 |
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| 作者单位： | 1. 同济大学环境科学与工程学院 污染控制与资源化研究国家重点实验室 上海 200092,1. 同济大学环境科学与工程学院 污染控制与资源化研究国家重点实验室 上海 200092,1. 同济大学环境科学与工程学院 污染控制与资源化研究国家重点实验室 上海 200092,2. 同济大学环境科学与工程学院 长江水环境教育部重点实验室 上海 200092,1. 同济大学环境科学与工程学院 污染控制与资源化研究国家重点实验室 上海 200092 |
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| 基金项目： | 国家杰出青年科学基金(51625804) |
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| 摘 要： | 代谢组学以完整的生物体为研究对象,运用合适的分析测试手段检测靶向或非靶向代谢物,结合统计模型进行分析解释。随着微藻研究的深入,微藻与代谢组学结合探究分子作用机理的研究日益增多。本文总结代谢组学的发展概况、研究流程及常用分析技术特点和代谢组学在微藻领域的研究进展,展望代谢组学在微藻研究的应用前景与发展趋势,并提出实际应用中所面临的困难与挑战。
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| 关 键 词： | 代谢组学，微藻，分析流程，应用研究 |
Metabolomics and its application in the study of microalgae |
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| REN Li,ZHANG Yong-Gang,MA Rui,ZHOU Xue-Fei and ZHANG Ya-Lei.Metabolomics and its application in the study of microalgae[J].Microbiology,2018,45(1):166-172. |
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| Authors: | REN Li ZHANG Yong-Gang MA Rui ZHOU Xue-Fei and ZHANG Ya-Lei |
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| Institution: | 1. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China,1. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China,1. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China,2. Key Laboratory of Yangtze River Aquatic Environment of the Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China and 1. State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China |
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| Abstract: | Metabolomics studies the complete biological system, to detect target or non-target metabolites by appropriate analytical methods and to interpret metabolites in combination with statistical models. Microalgae studies focus now increasingly on molecular mechanism by means of metabolomics. Here, we summarize the development of metabolomics, the research process and the characteristics of common analytical techniques and the progress of metabolomics in the field of microalgae. We also discuss the prospect of metabolomics in microalgae research, and challenges in practical application. |
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| Keywords: | Metabolomics Microalgae Analysis process Application |
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