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Shtyrlin Valery G. Borissenok Valery A. Serov Nikita Yu. Simakov Vladimir G. Bragunets Vyacheslav A. Trunin Ivan R. Tereshkina Irina A. Koshkin Sergey A. Bukharov Mikhail S. Gilyazetdinov Edward M. Shestakov Evgeny E. Sirotkina Anna G. Zakharov Alexey V. 《Origins of life and evolution of the biosphere》2019,49(1-2):1-18
Origins of Life and Evolution of Biospheres - Syntheses under shock in nitrogen bubbled samples of the water – formamide – bicarbonate – sodium hydroxide system at... 相似文献
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I S Komolov A A Bulatov Iu K Trunin S Iu Serpukhovitin E I Marova I I Dedov 《Biulleten' eksperimental'no? biologii i meditsiny》1992,113(4):421-424
This paper describes the development of method of preparing cell suspension obtained from surgical material of patients with pituitary adenomas and acromegaly as well as the procedure of subsequent long-term cultivation in monolayers of the cells isolated. As judged by visual inspection and measurement of growth hormone and prolactin secretion, tumor pituitary cells kept viability and functional activity for at least 6 days of growing in vitro. Immunocytochemical visualization of somato- and lactotrophs of the same histological preparations permitted us to show that vast majority of cultured cells is represented by somatotrophs; however, a small portion of cell population is represented by lactotrophs and lactosomatotrophs. The peculiarities of cytoarchitectonics in two types of cell cultures of human somatotropinomas were studied. 相似文献
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A A Bulatov I S Komolov N B Smirnova Iu K Trunin S Iu Serpukhovitin L K Dzeranova E I Marova I I Dedov 《Biulleten' eksperimental'no? biologii i meditsiny》1992,113(4):406-409
The effects of somatostatin and thyroliberin (thyrotropin-releasing hormone; TRH) on growth hormone (GH) and prolactin (PRL) secretion were studied in short-term (0.5-3h) or long-term (21-24h) incubations using monolayer cell cultures of somatotropin obtained from surgical material of patients with acromegaly. High sensitivity of both GH and PRL release to inhibitory action of somatostatin (10(-11) M) was established. We could not reveal the unambiguous influence of TRH on somatotropic function in the in vivo and in vitro conditions, as compared to the action of this tripeptide on PRL secretion. The results obtained permit us to propose that cell cultures of pituitary adenomata represent adequate and convenient models for studying the pathogenesis of tumor processes in the pituitary gland and for the development of new procedures of pharmacotherapy. 相似文献
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V N Ustinov M A Trunin M F Stoma 《Biulleten' eksperimental'no? biologii i meditsiny》1987,103(2):141-143
The changes in the frequency parameters of the basic electrical gastric rhythm were studied with the application of cutaneous electrodes in men. The study has demonstrated that the frequency parameters of the basic electrical gastric rhythm are dependent on the organ's functional state. The frequency parameters can be used for the identification of the gastric functional state both in healthy and sick subjects. 相似文献
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