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Katri Lindfors Keijo M Viiri Marjo Niittynen Taisto YK Heinonen Markku M?ki Heikki Kainulainen 《BMC genomics》2003,4(1):53
Background
We have previously set up an in vitro mesenchymal-epithelial cell co-culture model which mimics the intestinal crypt villus axis biology in terms of epithelial cell differentiation. In this model the fibroblast-induced epithelial cell differentiation from secretory crypt cells to absorptive enterocytes is mediated via transforming growth factor-β (TGF-β), the major inhibitory regulator of epithelial cell proliferation known to induce differentiation in intestinal epithelial cells. The aim of this study was to identify novel genes whose products would play a role in this TGF-β-induced differentiation. 相似文献3.
The assessment of heart rate variability (HRV) thresholds (HRVTs) as an alternative of Ventilatory thresholds (VTs) is a relatively new approach with increasing popularity which has not been conducted in cross-country (XC) skiing yet. The main purpose of the present study was to assess HRVTs in the five main XC skiing-related techniques, double poling (DP), diagonal striding (DS), Nordic walking (NW), V1 skating (V1), and V2 skating (V2).Ten competitive skiers completed these incremental treadmill tests until exhaustion with a minimum of one to two recovery days in between each test. Ventilatory gases, HRV and poling frequencies were measured. The first HRV threshold (HRVT1) was assessed using two time-domain analysis methods, and the second HRV threshold (HRVT2) was assessed using two non-time varying frequency-domain analysis methods. HRVT1 was assessed by plotting the mean successive difference (MSD) and standard deviation (SD) of normalized R-R intervals to workload. HRVT1 was assessed by plotting high frequency power (HFP) and the HFP relative to respiratory sinus arrhythmia (HFPRSA) with workload. HRVTs were named after their methods (HRVT1-SD; HRVT1-MSD; HRVT2-HFP; HRVT2-HFP-RSA). The results showed that the only cases where the proposed HRVTs were good assessors of VTs were the HRVT1-SD of the DS test, the HRVT1-MSD of the DS and V2 tests, and the HRVT2-HFP-RSA of the NW test. The lack of a wider success of the assessment of HRVTs was reasoned to be mostly due to the high entrainment between the breathing and poling frequencies. As secondary finding, a novel Cardiolocomotor coupling mode was observed in the NW test. This new Cardiolocoomtor coupling mode corresponded to the whole bilateral poling cycle instead of corresponding to each poling action as it was reported to the date by the existing literature. 相似文献
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Plant colonization of bare peat surface - relative importance of seed availability and soil 总被引:2,自引:0,他引:2
A field survey on two former peat harvesting sites of similar successional age revealed a marked difference in species composition and a 30-fold difference in biomass of the established vegetation Based on this observation, a field experiment in which the substrate was changed between sites was conducted to examine whether the differences in revegetation were mainly a consequence of differences in seed supply or in substrate quality After three growing seasons, a many hundred-fold difference in plant biomass existed between the transplanted and control plots with the same substrate, but only a small difference between the plots with a different substrate within the site Biological activity in the substrate of the slowly revegetating site (site 1) increased when transported to the more rapidly revegetating site (site 2), while the opposite was true when substrate from site 2 was transported to site 1 The sites differed in the rate of N mineralization, and particularly in nitrification Despite the differences in substrate quality between the two sites, seed supply appeared to be the major factor controlling colonization The impact of the soil factors on plant establishment was, however, considered to be large enough to act as an additional controlling factor 相似文献
7.
Stephen J Martin Emma Vitikainen Heikki Helanter? Falko P Drijfhout 《Proceedings. Biological sciences / The Royal Society》2008,275(1640):1271-1278
Distinguishing nest-mates from non-nest-mates underlies key animal behaviours, such as territoriality, altruism and the evolution of sociality. Despite its importance, there is very little empirical support for such a mechanism in nature. Here we provide data that the nest-mate recognition mechanism in an ant is based on a colony-specific Z9-alkene signature, proving that surface chemicals are indeed used in ant nest-mate recognition as was suggested 100 years ago. We investigated the cuticular hydrocarbon profiles of 10 Formica exsecta colonies that are composed almost entirely of a Z9-alkene and alkane component. Then we showed that worker aggression is only elicited by the Z9-alkene part. This was confirmed using synthetic Z9-alkene and alkane blends matched to the individual colony profiles of the two most different chemical colonies. In both colonies, only glass beads with 'nest-mate' alkene profiles received reduced aggression. Finally, changing the abundance of a single Z9-alkene on live ants was shown to significantly increase the aggression they received from nest-mates in all five colonies tested. Our data suggest that nest-mate discrimination in the social insects has evolved to rely upon highly sensitive responses to relatively few compounds. 相似文献
8.
Recent studies suggest that evergreen plants may maintain their photosynthetic capacity through the winter. Since mild winters
are predicted to be more frequent in the future, the metabolic activity of plants is also likely to increase. The aim of the
present study was to assess how various environmental factors, such as temperature, photoperiod and preceding frost, affect
the recovery of photosynthesis during a mild spell in winter. The recovery of photosynthesis was studied in a series of growth
chamber experiments where the overwintering of lingonberry (Vaccinium vitis-idaea) was interrupted by an intermittent warm spell of 1 week during different phases of winter. Rapid activation was observed
in all the experiments during the first 3–4 days. No obvious effects of the phase of winter or photoperiod on the recovery
of photosynthesis were observed, but a severe freezing treatment prior to the warm spell retarded the recovery significantly.
Once recovered, however, lingonberry was able to maintain high rates of photosynthesis even at near-freezing temperatures,
which prevail in their natural sub-nivean environment. The apparent quantum yield of photosynthesis remained high through
the winter for lingonberry. This may prove advantageous for evergreen dwarf shrubs which overwinter in dim environments under
snow. 相似文献
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Lei Chen Jian‐Guo Huang Qianqian Ma Heikki Hnninen Francine Tremblay Yves Bergeron 《Global Change Biology》2019,25(3):997-1004
Contrary to the generally advanced spring leaf unfolding under global warming, the effects of the climate warming on autumn leaf senescence are highly variable with advanced, delayed, and unchanged patterns being all reported. Using one million records of leaf phenology from four dominant temperate species in Europe, we investigated the temperature sensitivities of spring leaf unfolding and autumn leaf senescence (ST, advanced or delayed days per degree Celsius). The ST of spring phenology in all of the four examined species showed an increase and decrease during 1951–1980 and 1981–2013, respectively. The decrease in the ST during 1981–2013 appears to be caused by reduced accumulation of chilling units. As with spring phenology, the ST of leaf senescence of early successional and exotic species started to decline since 1980. In contrast, for late successional species, the ST of autumn senescence showed an increase for the entire study period from 1951 to 2013. Moreover, the impacts of rising temperature associated with global warming on spring leaf unfolding were stronger than those on autumn leaf senescence. The timing of leaf senescence was positively correlated with the timing of leaf unfolding during 1951–1980. However, as climate warming continued, the differences in the responses between spring and autumn phenology gradually increased, so that the correlation was no more significant during 1981–2013. Our results further suggest that since 2000, due to the decreased temperature sensitivity of leaf unfolding the length of the growing season has not increased any more. These finding needs to be addressed in vegetation models used for assessing the effects of climate change. 相似文献