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Soogarun S Sangvanich P Chowbumroongkait M Jiemsup S Wiwanikit V Pradniwat P Palasuwan A Pawinwongchai J Chanprasert S Moungkote T 《Journal of biochemical and molecular toxicology》2008,22(4):225-229
Green pit viper venom has major effect on the hematological system having a thrombin-like effect. Thus, this study is designed to analyze the composition of Trimeresurus albolabris venom by performing gel filtration and LC/MS-MS. The purified protein was then digested by trypsin, and the tryptic fragments were analyzed by iontrap spectrophotometry. This study found four types of proteins, namely jerdonitin, stejaggregin-A beta chain-1, stejnobin, and stejnihagin-A, as the components of T. albolabris venom. All of these toxins played a greater or lesser role in clot formation or otherwise contributed to cross-reactions in antivenom production. 相似文献
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