Repeated pre-training sleep restriction in adolescent rats impaired spatial performance

Sleep and Biological Rhythms - Chronic sleep deprivation (SD) is an overwhelming problem in young students. Firstly, we investigated whether different levels of pre-training SD had effects on...     

APOBEC3G与Vif在HIV-1感染中的作用

载脂蛋白B mRNA编辑催化多肽样（apolipoprotein B mRNA-editing catalytic polypeptide-like,APOBEC）蛋白是一组胞嘧啶脱氨基酶,具有天然的抗病毒活性,对多种病毒具有抑制作用,特别是逆转录病毒. APOBEC3蛋白能够抑制人类免疫缺陷病毒(HIV-1)的感染,其中APOBEC3G和APOBEC3F的作用最强. APOBEC3G能够通过胞嘧啶脱氨基作用和非胞嘧啶脱氨基作用抑制病毒感染. HIV-1病毒感染因子(Vif) 蛋白主要经泛素-蛋白酶体途径介导APOBEC3G降解,从而拮抗其抗病毒作用. APOBEC3G和Vif之间相互作用的研究对于寻求新的抗HIV治疗靶点具有重要意义.     

Carex tenuirostrata (Cyperaceae), a new species of section Confertiflorae from Zhejiang, China

Carex tenuirostrata, a new species of C. sect. Confertiflorae, is described from Pingyang and Putuo counties of Zhejiang province, China. It is morphologically similar to C. pseudodispalata, but differs in its androgynous lateral spikes; distended perigynia attenuately contracted into a short beak at the apex; ellipsoid-obovoid achenes contracted into a slender beak at the apex; and long-sheathed lower bracts. Scanning electron microscope (SEM) photographs of the achenes of the new species and C. pseudodispalata are provided for comparison.