In Sri Lanka, termination of pregnancy, other than in extreme circumstances, is strictly illegal. Among the public and large
sections of the medical community there is widespread support for some degree of liberalization of the law, particularly where
this relates to serious genetic conditions which can be identified prenatally. Tension emerges out of a publicly maintained
conservatism on issues of abortion on the one hand and a growing disconnection from unregulated practices of termination in
the private sector on the other. Social science approaches have much to contribute when understanding the ‘therapeutic gap’
that opens up and, in particular, the way that local ideas of fate, destiny and how suffering might be ameliorated become
blended with the predictive power of genetic testing. 相似文献
Water buffalo (Bubalus bubalis) are affected by high rates of embryonic mortality and abortion related to infectious diseases and non-infectious factors. A number of viral and bacterial infections have been associated with reproductive failure, but there is limited information on the role of chlamydial infections.
In order to investigate the presence and the role of Chlamydiaceae in water buffalo a retrospective study was performed in a herd with a history of reproductive failure. During an 11-month period, the pregnant heifers suffered an abortion rate of 36.8% between the 3rd and 7th month of pregnancy. Antibodies to Chlamydiaceae were detected in 57% of the aborted cows, and in 0% of the overtly healthy cows used as control. By a nested-PCR assay, three of 14 vaginal swabs from aborted animals tested positive for Chlamydophila agents and, additionally, three out of seven aborted fetuses tested positive for Chlamydophila spp., with two being co-infections by Cp. abortus and Cp. pecorum and one being characterised as Cp. abortus. Sequence analysis of the amplicons confirmed the results of the nested-PCR. The presence of anti-Chlamydiaceae antibodies in more than half of the aborting animals (P < 0.002) and the detection of Chlamydophila agents in several fetal organs and in the vaginal swabs are consistent with the history of abortions observed in the herd and suggest an abortifacient role by Chlamydophila spp. in water buffalo (B. Bubalis) herds. 相似文献
The proband was a 22-year-old woman who had two spontaneous abortions in the first trimester of pregnancy. She had a consanguineous marriage with no history of malformation or developmental disorders in the family. Her gynecological examination was normal. Chromosome analysis of the family showed two different katyotypes 46,XY,t(1;16)(p22;p13) and 46,XX,t(1;16)(q24;q24) using high-resolution banding (HRB). Proband's family was also examined for chromosome analysis. A t(1;16)(p22;p13) was found in the husband's father and other relatives, and a t(1;16)(q24;q24) translocation in the proband's family. This second tanslocation is not found in her parents. 相似文献
In 1989 a new gelada baboon (Theropithecus gelada) population was found in Arsi, on the opposite side of the Rift Valley to that of the known gelada populations of Semien
and Showa. Previous comparisons of units of the band at Gado Goro, Arsi, in the same season in consecutive years, indicated
that unit structure is less stable among Arsi geladas as compared to the Semien population. Gelada units of the band at Gado-Goro
were studied for 7 months in order to investigate the processes of social changes. Changes in unit structure were observed.
Provisioning was carried out for 1.5 months at the beginning of the 7-month study period, in order to capture and obtain blood
samples from the geladas. Following this, changes in male leadership of some units were observed, presumably as a consequence
of the capture. However, natural changes also occurred. One change in unit structure occurred after a female gave birth, and
changes in another unit occurred after the disappearance of the leader male. These changes involved female desertion of a
unit, her subsequent transfer to a male unit, and culminated in the formation of a unit consisting of one female and one male.
One successful and one attempted case of unification of units, and one case of change of a unit leader male are reported.
These changes occurred among eight resident units in a period of 7 months (196 female months). Though the types of social
changes were not much different from previous observations in Semien National Park, their frequencies seemed to be much higher.
The characteristics of Arsi gelada social changes are proposed to be related to the small size of the units. We also describe
a new confirmed case and one suspected case of infanticide, as well as one case of abortion at the time of male leader change. 相似文献
The parasite Neospora caninum is an important cause of abortion in cattle world-wide. Chronically infected dams transmit the parasite transplacentally and infected foetuses may be aborted or born chronically infected but clinically normal. Chronically infected cows repeatedly transmit the parasite to foetuses in several pregnancies and some may abort more than once suggesting that the immune response in these cattle is compromised during pregnancy. To investigate the nature of the immune response in chronically infected cattle, five naturally, chronically infected cows were challenged with N. caninum tachyzoites at 10 weeks of gestation. No foetopathy occurred and all five delivered live calves at full-term. In four naive pregnant cows challenged at the same time, all four foetuses died within 3-5 weeks of challenge. Of the five live calves born to the chronically infected challenged cows, three were transplacentally infected with N. caninum. The kinetics of the maternal anti-N. caninum antibody responses during gestation suggested that these transplacental infections were not the result of the superimposed challenge, but the result of the recrudescence of the maternal chronic infection-which occurred concurrently in non-challenged, chronically infected pregnant controls. These data provide the first experimental evidence that protective immunity occurs in neosporosis. They also suggest that whilst immunity to a pre-existing infection will protect against an exogenous challenge, this protective immunity will not prevent transplacental infection. This implies that a subtle form of concomitant immunity exists in chronically infected cattle and has important implications for vaccine development. 相似文献
Plants of white clover ( Trifolium repens L.) cv. Olwen were grown in an open glasshouse maintained at a mean temperature of 20oC and ovule growth and seed production measured. Differences in the rate of growth of ovules within ovaries were observed as early as 2 days after pollination. Ovules reached a maximum size after 8 days with the smallest only half the size of the largest. After 8 days, the smallest ovules became flaccid and shrivelled. Ovule position within the ovary had little effect on the frequency of seed set and although there was an apparently higher probability that central ovules produced a seed than those nearer the peduncle or style this was not statistically significant. Inflorescence position and floret position on the inflorescence had a significant effect on the number of seeds per floret and seed weight; the first formed inflorescences and the first florets to be pollinated on each inflorescence had more seeds per floret and heavier seeds and fewer florets with no seed than later pollinated florets. There were also differences between florets within the same whorl. The role of a number of factors which may influence floret site utilisation are discussed. 相似文献