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551.
Brucellosis is a zoonosis caused by Brucella ,with an acute or chronic clinical infection .Clinical manifestations of brucellosis are various or atypical ,and it is easily misdiagnosed and miss-diagnos... 相似文献
552.
To clarify crucial key micro-RNAs and mRNAs associated with hand, foot, and mouth disease (HFMD) virus infection, we conducted this bioinformatics analysis from four GEO datasets. The following datasets were used for the analysis: , GSE85829, GSE94551, and GSE52780. Differentially expressed genes (DEGs) were acquired, and the analysis of functional and pathway enrichment and the relative regulatory network were conducted. After screening common differentially expressed miRNAs (DE-miRNAs), five key miRNAs were acquired: miR-100-3p, miR-125a-3p, miR-1273g-3p, miR-5585-3p, and miR-671-5p. There were three common enriched GO terms between miRNA-derived prediction and mRNA-derived analysis: biosynthetic process, cytosol, and nucleoplasm. There was one common KEGG pathway, i.e., cell cycle shared between miRNA-based and mRNA-based enrichment. Using TarBase V8 in DIANA tools, we acquired 1,520 potential targets (mRNA) from the five key DE-miRNAs, among which the159 DE-mRNAs also included 11 DEGs. These common DEGs showed a PPI network mainly connected by SMC1A, SMARCC1, SF3B3, LIG1, and BRMS1L. Together, changes in five key miRNAs and 11 key mRNAs may play crucial roles in HFMD progression. A combination of these roles may benefit the early diagnosis and treatment of HFMD.Key words: GSE45589HFMD, micro-RNA, protein-protein interaction, microarray, regulatory network 相似文献
553.
作物连作障碍的成因与机制及其消减策略 总被引:3,自引:0,他引:3
在论述作物连作障碍危害的基础上,从植物营养学、土壤学、微生物学角度分析产生作物连作障碍的原因与形成机理,认为作物连作障碍形成是复杂的根际生物学过程,它是由连作作物根系分泌物介导引起根际土壤微生物结构失衡,导致病原微生物增多,土壤酸化和营养封存综合作用的结果。据此,进一步就连作障碍防治措施及修复技术进行归纳总结,为有效克服作物连作障碍提供技术借鉴。 相似文献
554.
555.
Robust optimal extrapolation designs 总被引:1,自引:0,他引:1
556.
为了解睡莲属(Nymphaea)植物开花的日变化规律,以广州华南农业大学湿地公园的睡莲属植物为对象进行观察和分析。结果显示,晚上开花类的热带睡莲,其日变化是花朵于晚上开放并持续至第二天上午,白天开花类的热带睡莲和耐寒睡莲,其开放时间为白昼,开放时间因种类不同而有所差异。白天开花的热带睡莲‘独立’(Nymphaea‘Independence’)和耐寒睡莲‘科罗拉多’(Nymphaea‘Colorado’)单朵花期3~4 d,耐寒睡莲墨西哥黄睡莲(N.mexicana)单朵花期2 d,雌雄蕊先后成熟以达到异花授粉的目的,单朵睡莲开放期间雄蕊群呈现不同形态。‘独立’睡莲呈现日出而开,日落则合的开花生物钟,10月至12月,光照时间缩短导致‘独立’睡莲开闭节律缩短。观察结果可为园林水景中睡莲属植物配置提供准确的数据支持。 相似文献
557.
目的 通过对比对照组和太极拳运动组,评价太极拳运动在早中期帕金森病患者康复作用。方法 45例帕金森病患者随机分为:对照组(n=15),不接受干预;太极拳1组(n=15)采用24式简化太极拳练习,40 min/次,3次/周;太极拳2组(n=15)采用24式简化太极拳练习,60 min/次,3次/周。在基线、12周、24周运动后采用患者跌倒功效量表(FES)、起立-行走计时测试(TUGT)、Berg平衡量表评分(BBS)、统一帕金森病评定量表(UPDRS) Ⅲ评分、汉密尔顿焦虑抑郁量表评分(HAMD、HAMA)、匹兹堡睡眠质量指数评分(PSQI)进行评估。结果 太极拳1组,24周对比基线在TUGT、BBS评分的改善上有统计学意义(P<0.05)。太极拳2组,24周对比基线在TUGT、 BBS评分的改善上有统计学意义(P<0.05),24周对比12周在TUGT的改善上有统计学意义(P<0.05)。结论 太极拳运动可以改善早中期帕金森病患者的平衡障碍,可降低跌倒风险。 相似文献
558.
Modelled effects of precipitation on ecosystem carbon and water dynamics in different climatic zones
DIETER GERTEN YIQI LUO GUERRIC Le MAIRE WILLIAM J. PARTON CINDY KEOUGH ENSHENG WENG CLAUS BEIER PHILIPPE CIAIS WOLFGANG CRAMER JEFFREY S. DUKES PAUL J. HANSON ALAN A. K. KNAPP SUNE LINDER DAN NEPSTAD LINDSEY RUSTAD ALWYN SOWERBY 《Global Change Biology》2008,14(10):2365-2379
The ongoing changes in the global climate expose the world's ecosystems not only to increasing CO2 concentrations and temperatures but also to altered precipitation (P) regimes. Using four well-established process-based ecosystem models (LPJ, DayCent, ORCHIDEE, TECO), we explored effects of potential P changes on water limitation and net primary production (NPP) in seven terrestrial ecosystems with distinctive vegetation types in different hydroclimatic zones. We found that NPP responses to P changes differed not only among sites but also within a year at a given site. The magnitudes of NPP change were basically determined by the degree of ecosystem water limitation, which was quantified here using the ratio between atmospheric transpirational demand and soil water supply. Humid sites and/or periods were least responsive to any change in P as compared with moderately humid or dry sites/periods. We also found that NPP responded more strongly to doubling or halving of P amount and a seasonal shift in P occurrence than that to altered P frequency and intensity at constant annual amounts. The findings were highly robust across the four models especially in terms of the direction of changes and largely consistent with earlier P manipulation experiments and modelling results. Overall, this study underscores the widespread importance of P as a driver of change in ecosystems, although the ultimate response of a particular site will depend on the detailed nature and seasonal timing of P change. 相似文献