硒-铁蛋白电化学反应器储存含磷化合物的研究

由透析袋、硒－铁蛋白、恒流泵、电导仪、磁力搅拌器及电化学系统等构成成硒－铁蛋白电化学反应器。该反应器可储存流动水体中微量含磷化合物于铁蛋白的蛋白壳内,其储存量高低与流动水体中的含磷化合物含量成正比关系。经硒改造后的硒－铁蛋白能提高有机磷农药的储存量,其储存能力与铁蛋白种类无关,可能与铁蛋白自身构象有关。     

The efficacy of a technology-based system in a short-term behavioral weight loss intervention

Objective: The objective was to examine the efficacy of adding a technology‐based program to an in‐person, behavioral weight loss intervention. Research Methods and Procedures: Fifty‐seven subjects (BMI = 33.1 ± 2.8 kg/m²; age = 41.3 ± 8.7 years) participated in a 12‐week intervention with random assignment to Standard In‐Person Behavioral Weight Control Program (SBWP) or Intermittent or Continuous Technology‐Based Program (INT‐TECH, CON‐TECH). SBWP subjects received seven individualized weight loss sessions encouraging dietary and exercise modifications. INT‐TECH and CON‐TECH subjects received all SBWP components; additionally, these groups used a SenseWear Pro Armband (BodyMedia, Inc.) to monitor energy expenditure and an Internet‐based program to monitor eating behaviors. These features were used by INT‐TECH subjects during weeks 1, 5, and 9 and CON‐TECH subjects weekly throughout the intervention. Results: Intent‐to‐treat analysis revealed weight loss of 4.1 ± 2.8 kg, 3.4 ± 3.4 kg, and 6.2 ± 4.0 kg, for SBWP, INT‐TECH, and CON‐TECH groups, respectively (CON‐TECH > INT‐TECH, p ≤ 0.05). Discussion: These results indicate that the technology‐based program needs to be used continuously throughout the intervention period to significantly impact weight loss. Future studies should examine the long‐term and independent effect of this technology on weight loss, and for whom this intervention format is most effective.     

Presence of robust circadian clock oscillation under constitutive over-expression of mCry1 in rat-1 fibroblasts

In mammals, mCRY proteins are essential and are major negative elements in circadian feedback loops. In this study, robust circadian clock oscillation was present even under conditions with constitutive over-expression of mCry1 in rat-1 cells. Rat-1 cells were produced to stably express mPer2 promoter-driven luciferase reporter, in which mCry1 was overexpressed under a tetracycline-dependent gene expression (Tet-On) system. Using these cells, we show that circadian clock oscillations in rat-1 fibroblasts persist when the mCRY1 protein constitutively accumulates in the nuclei.     

基于蓝牙4.0的便携式睡眠监测仪的研制

目的:实时监测睡眠状况,从而帮助人们特别是老人找到影响睡眠的原因。方法:设计了一个低功耗便携式睡眠监测仪,它是通过加速度传感器采集腕动信号、蓝牙4.0低功耗无线传输、Micro-SD卡存储、上位机显示等实现对睡眠状态的检测。为了验证睡眠监测仪的准确性,本文采用了视频分析方法,并且对不同人群进行监测。结果:研制的睡眠监测仪具有便携低功耗等特点,能够准确监测睡眠状态。结论:睡眠监测仪的研制对使用者特别是老人帮助很大,能够帮助使用者方便适时了解自己的睡眠状况,找到影响睡眠原因和改善睡眠质量方法。     

基于OCT技术的鼠皮肤激光热损伤修复过程的监测

采用Er:YAG激光(波长为2 940 nm,能量密度为:2.5 J/cm2单光斑,扫描次数为4)照射活体小白鼠皮肤,利用光学相干层析成像(optical coherence tomography,OCT)技术在活体小鼠上观察其皮肤组织在激光作用之前及作用之后光热损伤修复的整个过程,得到了激光光热作用下引起损伤的皮肤组织在此过程中皮肤光学特性参数的变化情况,发现皮肤修复过程中光学参数有显著差异,并分析了这些差异引起的原因,以揭示激光美容中并发症主要因素。     

Learning-aided predictor integration for system performance prediction

The integration of multiple predictors promises higher prediction accuracy than the accuracy that can be obtained with a single predictor. The challenge is how to select the best predictor at any given moment. Traditionally, multiple predictors are run in parallel and the one that generates the best result is selected for prediction. In this paper, we propose a novel approach for predictor integration based on the learning of historical predictions. Compared with the traditional approach, it does not require running all the predictors simultaneously. Instead, it uses classification algorithms such as k-Nearest Neighbor (k-NN) and Bayesian classification and dimension reduction technique such as Principal Component Analysis (PCA) to forecast the best predictor for the workload under study based on the learning of historical predictions. Then only the forecasted best predictor is run for prediction. Our experimental results show that it achieved 20.18% higher best predictor forecasting accuracy than the cumulative MSE based predictor selection approach used in the popular Network Weather Service system. In addition, it outperformed the observed most accurate single predictor in the pool for 44.23% of the performance traces.

双侧颈总动脉结扎对大鼠学习记忆相关脑区血流量的影响

目的为建立双侧颈总动脉结扎致大鼠血管性痴呆模型,观察了大鼠双侧颈总动脉结扎后不同脑区脑血流量的影响。方法采用激光多普勒血流仪,测定麻醉大鼠双侧颈总动脉结扎后１０ｍｉｎ内不同脑区脑血流量变化。结果大鼠双侧颈总动脉结扎后,平均脑血流量减少额区６７８３％、顶区５６８２％、枕区１６１６％、Ｍｙｎｅｒｔ基底核５１２１％、尾壳核４１１８％,海马ＣＡ１５１８３和海马ＣＡ２４１２１。结论大鼠双侧颈总动脉结扎后与学习记忆有关的脑区脑血流量均显著下降