| 基于OCT技术的鼠皮肤激光热损伤修复过程的监测 |
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| 引用本文： | 何友武,李雪芳,吴淑莲,李晖,谢树森.基于OCT技术的鼠皮肤激光热损伤修复过程的监测[J].激光生物学报,2007,16(2):163-166. |
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| 作者姓名： | 何友武 李雪芳 吴淑莲 李晖 谢树森 |
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| 作者单位： | 福建师范大学物理与光电信息科技学院,医学光电科学与技术教育部重点实验室,福建,福州,350007 |
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| 基金项目： | 教育部高校优秀青年教师资助计划
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教育部跨世纪优秀人才培养计划 |
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| 摘 要： | 采用Er:YAG激光(波长为2 940 nm,能量密度为:2.5 J/cm2单光斑,扫描次数为4)照射活体小白鼠皮肤,利用光学相干层析成像(optical coherence tomography,OCT)技术在活体小鼠上观察其皮肤组织在激光作用之前及作用之后光热损伤修复的整个过程,得到了激光光热作用下引起损伤的皮肤组织在此过程中皮肤光学特性参数的变化情况,发现皮肤修复过程中光学参数有显著差异,并分析了这些差异引起的原因,以揭示激光美容中并发症主要因素。
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| 关 键 词： | 光学相干层析成像技术 热损伤 监测 |
| 文章编号： | 1007-7146（2007）02-0163-04 |
| 收稿时间： | 2006-06-22 |
| 修稿时间： | 2006-12-06 |
Monitoring the Process of Tissue Healing of Mouse Skin in vivo after Laser Irradiation Based on Optical Coherence Tomography |
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| HE You-wu,LI Xue-fang,WU Shu-lian,LI Hui,XIE Shu-sen.Monitoring the Process of Tissue Healing of Mouse Skin in vivo after Laser Irradiation Based on Optical Coherence Tomography[J].ACTA Laser Biology Sinica,2007,16(2):163-166. |
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| Authors: | HE You-wu LI Xue-fang WU Shu-lian LI Hui XIE Shu-sen |
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| Institution: | Key Laboratory of OptoElectronic Science and Technology for Medicine, Ministry of Education, School of Physics and OptoElectronics Technology, Fujian Normal University, Fuzhou 350007, Fujian, China |
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| Abstract: | Er:YAG laser(2 940 nm,2.5 J/cm2,single spot, 4 times) was irradiation on a mouse skin in vivo,and the skin which before irradiation and the process of renovating scathe that irradiated after Er:YAG laser were observed by an optical coherence tomography(OCT).The results indicate that the optical parameters of post-laser irradiation tissue have changed distinctly.The reasons concerning some complications were analyzed by the optical parameters' changes and the major factors of the complications in laser skin rejuvenation were expected to be found. |
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| Keywords: | optical coherence tomography(OCT) thermal damage monitor |
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