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121.
Central nervous system (CNS) maintains a high level of metabolism, which leads to the generation of large amounts of free radicals, and it is also one of the most vulnerable organs to oxidative stress. Emerging evidences have shown that, as the key homeostatic cells in CNS, astrocytes are deeply involved in multiple aspects of CNS function including oxidative stress regulation. Besides, the redox level in CNS can in turn affect astrocytes in morphology and function. The complex and multiple roles of astrocytes indicate that their correct performance is crucial for the normal functioning of the CNS, and its dysfunction may result in the occurrence and progression of various neurological disorders. To date, the influence of astrocytes in CNS oxidative stress is rarely reviewed. Therefore, in this review we sum up the roles of astrocytes in redox regulation and the corresponding mechanisms under both normal and different pathological conditions.  相似文献   
122.
施硼和赤霉素对‘李广杏’坐果率及果实品质的影响   总被引:1,自引:0,他引:1  
该研究以8年生盛果期的‘李广杏’植株为试材,于花蕾膨大期喷施0.1%(P1)、0.3%(P2)和0.5%(P3)硼砂和盛花初期喷施50(C1)、100(C2)和150 mg/L(C3)赤霉素,测定不同处理下李广杏的坐果率、果实品质及营养生长指标的变化,并用主成分分析不同处理的效果进行综合评价,为敦煌寒旱区‘李广杏’的栽培提供理论依据。结果表明:(1)‘李广杏’叶面积增长量在C1浓度处理下显著高于CK,不同浓度的硼处理对其均具有抑制作用,但C1、P2浓度下新稍生长量高于其他处理。(2)适宜浓度的硼和赤霉素处理可一定程度减少‘李广杏’花的败育率,从而有效提高果树的坐果率,其中硼处理以P3浓度下最优,但P3与P2处理下坐果率无显著差异,赤霉素处理以C2浓度下最优。(3)适宜浓度硼和赤霉素能够明显提高‘李广杏’果实品质,C1浓度处理下的果实糖酸比、可溶性固形物含量显著高于CK,P2处理下的果实维生素C、可滴定酸含量显著高于其他处理;适宜浓度赤霉素和硼对果实的单果重、果形指数、侧径有明显的促进作用。(4)主成分分析结果显示,各处理效果的综合得分由高到低依次为P2(1.20)>C2(0.91)>P1(0.13)>C1(-1.01)>CK(-1.68)>P3(-2.13)>C3(-7.76);果实可溶性糖、可溶性蛋白、糖酸比等主成分占比较高,可作为评价‘李广杏’果实品质的重要依据。研究发现,花期喷施适宜浓度的硼和赤霉素可有效提高‘李广杏’果树的生长状况、坐果率及果实品质,且甘肃敦煌地区以花蕾膨大期喷施0.3%硼和盛花初期喷施100 mg/L赤霉素效果最佳。  相似文献   
123.
内蒙古自治区干旱脆弱性评价   总被引:3,自引:0,他引:3  
干旱带来的环境影响及经济损失,阻碍了地区的可持续发展。开展干旱脆弱性评价是合理制定区域规划与管理措施的前提条件。然而,国内目前鲜有以省或自治区为研究区域,以市级行政区域为尺度的自然-社会-经济耦合的干旱脆弱性研究。根据IPCC提出的干旱脆弱性评价模型,选取19个指标,在3个维度上(暴露度、敏感度和适应能力)对内蒙古自治区的12个盟市开展了干旱脆弱性评价。采用熵值法确定各指标权重,并用综合指数法和系统分类法计算干旱脆弱性指数并进行分类。研究结果表明,内蒙古自治区的干旱脆弱性呈现由东向西递减的趋势,与干旱脆弱性相关性最强的三个指标分别是第一产业GDP比例、人均可支配收入和第一产业从业人员比例。导致盟市干旱脆弱性的主要贡献因素为人口与人力因素和生态与水资源因素。减缓内蒙古自治区干旱脆弱性可以从加强草原保护建设和管理,合理规划盟市建设,减少人口的集中分布,调整产业结构,提供更多的非农牧就业岗位,加强职业技能培训,完善金融服务和医疗服务等方面入手,从而促进干旱区自然生态和社会经济的可持续发展。  相似文献   
124.
细菌小RNA是一类长度在50~500个核苷酸之间的不具有编码蛋白质功能,但具有转录后调控作用的RNA,在细菌中参与调控细菌多种生理和病理活动,如调节细菌代谢和毒力作用等过程。近年来,在结核分枝杆菌已经鉴定出近200种小RNA,并证明这些小RNA参与结核分枝杆菌的生理和病理过程。本文对结核分枝杆菌小RNA在细菌生长繁殖、毒力因子调控、细菌耐药和巨噬细胞内应激环境的适应等方面的作用进行综述。  相似文献   
125.
Giant ragweed (Ambrosia trifida, L. henceforth referred to as GR), an annual non‐native invasive weed, may cause health problems and can reduce agricultural productivity. Chemical control of GR in grasslands may have irreversible side effects on herbs and livestock. In an attempt to propose a solution to the harmful effects of GR on grasslands, this study explores the fate of its soil seed bank (SSB) and considers the physical control of its SSB reduction. By studying GR distributed in grasslands of the Yili Valley, Xinjiang, China, we measured the spatial and temporal changes in seed density, seed germination, dormancy, and death. We analyzed seed germination, dormancy, and death following different storage periods. The study analyzed population characteristics over time, including seed fate, and examined physical control methods for reducing the SSB density. The SSB of GR occurs in the upper 0–15 cm of soil in grasslands. Seed density in the SSB decreased by 68.1% to 82.01% from the reproductive growth period to the senescence period. More than 98.7% of the seeds were rotten, eaten, germinated, dispersed, or died within one year after being produced. The seed germination rate of the SSB decreased with the number of years after invasion. When stored for 0.5 or 3.5 years, seed germination rates fell by 40%, during which time seed death rate increased by almost 40%. When GR was completely eradicated for two consecutive years, the SSB and population densities decreased by >99%. The vast majority of GR seeds germinated or died within one year; the germination rate decreased significantly if the seeds were stored dry at room temperature for a long time. Newly produced seeds are the main source of seeds in the SSB. Therefore, thoroughly eradicating GR plants for several years before the seeds can mature provides an effective control method in grasslands.  相似文献   
126.
诺如病毒是导致人类急性胃肠炎的主要食源性致病原,由于变异快且缺乏稳健的体外细胞培养体系及小动物感染模型,限制了我们对该病原体的深入研究。近年来,可培养鼠源诺如病毒的发现、人源诺如病毒肠道细胞培养体系的开发,以及诺如病毒反向遗传操作体系的构建为系统研究该病原提供了有力工具,加深了我们对其复制机制、致病机理、病毒-宿主相互作用等的了解。本文主要综述了反向遗传学技术用于诺如病毒研究的工作进展,并讨论了该技术在诺如病毒分子病毒学研究、药物筛选和疫苗制备中的应用及发展前景,以期为诺如病毒防控策略的制定及药物靶点的挖掘提供有益参考,推进我国食品安全风险防控工作。  相似文献   
127.
Jiang  Lina  Fan  Zhengqi  Tong  Ran  Yin  Hengfu  Li  Jiyuan  Zhou  Xingwen 《Molecular biology reports》2021,48(5):3903-3912
Molecular Biology Reports - Camellia nitidissima Chi. is an ornamental plant of the genus Camellia L. Its flowers contain a lot of flavonoids and polyphenols. Flavonoid 3′-hydroxylase...  相似文献   
128.
Yu  Yifei  Hou  Kun  Ji  Tong  Wang  Xishu  Liu  Yining  Zheng  Yangyang  Xu  Jinying  Hou  Yi  Chi  Guangfan 《Molecular and cellular biochemistry》2021,476(5):2111-2124
Molecular and Cellular Biochemistry - MicroRNAs (miRNA), endogenous non-coding RNAs approximately 22 nucleotides long, regulate gene expression by mediating translational inhibition or mRNA...  相似文献   
129.
Li  Dongyang  Liu  Xiaoyu  Li  Tong  Wang  Xiaoran  Jia  Shuwei  Wang  Ping  Wang  Yu-Feng 《Neurochemical research》2021,46(4):980-991
Neurochemical Research - Oxytocin (OT) neuronal activity is the key factor for breastfeeding and it can be disrupted by mother-baby separation. To explore cellular mechanisms underlying OT neuronal...  相似文献   
130.
Purpose

Bio-jet fuel derived from energy crops has been promoted by governments around the world through policies such as the Carbon Offsetting and Reduction Scheme for International Aviation. The environmental impact and techno-economic analysis of bio-jet fuel are particularly pertinent to China because China is under huge pressure to reduce emissions, endeavouring to meet bio-economic goals.

Methods

An LCA study was conducted on the production of bio-jet fuel from jatropha and castor by estimating the well-to-wake emissions and its economic impact. The functional unit was 1 MJ of bio-jet fuel, and field survey data was used in inventory analysis. A scenario analysis was performed to measure diverse conditions, including the planting conditions, planting regions, allocation methods, and hydrogen sources. A techno-economic analysis that combined the production costs and co-product credits was performed to calculate the minimum bio-jet fuel selling price (MJSP) based on a plant capacity of 2400 metric tonnes of feedstock per day.

Results and discussion

Compared to the environmental impacts to the fossil jet fuel, the use of biofuel would reduce the majority environmental impacts by 36–85%, when a 1:1 displacement of fossil jet fuel is considered, though the human toxicity potential impact was 100% higher. The scenario analysis indicated that (i) planting castor in harsh and unevenly distributed conditions and jatropha in stable or fertile conditions can leverage their respective advantage; (ii) the global warming potential (GWP) from castor planting in the region of north-east China ranges from 34 to 48 g CO2 eq/MJ; (iii) the GWP produced through the steam methane reforming process can be reduced by 16–17%, using advances in technological processes. The MJSP for fuel produced from jatropha and castor under the basic scenario is estimated to be 5.68 and 4.66 CNY/kg, respectively, which falls within the current market price range of 4.5–7.5 CNY/kg.

Conclusions

Bio-jet fuel from jatropha and castor oilseeds offers potential environmental benefits if they can reduce fossil jet fuel on an energy-equivalent basis. However, these benefits are likely to be reduced by the rebound effect of the fuel market. Future research is needed to better understand the magnitude of the rebound effect in China and what policy interventions can be implemented to alleviate it. Scenario analysis demonstrated the feasibility and potential of bio-jet fuel development from multiple perspectives and technological progress are conducive to the realization of environmental protection policies.

  相似文献   
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