Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

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Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals

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Excessive proteostasis contributes to pathology in fragile X syndrome

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Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells

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Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells

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RAD51 protects human cells from transcription-replication conflicts

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Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

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Stn1-Ten1 and Taz1 independently promote replication of subtelomeric fragile sequences in fission yeast

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A small proportion of X-linked genes contribute to X chromosome upregulation in early embryos via BRD4-mediated transcriptional activation

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Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages

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Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

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B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells

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FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism

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Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax

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Fanconi anemia-associated chromosomal radial formation is dependent on POLθ-mediated alternative end joining

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Structural Basis for the High-Affinity Interaction between CASK and Mint1

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The origin and evolution of sex chromosomes,revealed by sequencing of the Silene latifolia female genome

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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

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AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay

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Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens

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