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Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells |
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| Institution: | 1. Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA;2. Center for RNA Biology, University of Rochester, Rochester, NY 14642, USA;3. Isotope Science Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan |
| Abstract: |  |
| Keywords: | fragile X syndrome protein human neuroblastoma cells FMRP RIP-seq footprinting SILAC-LC-MS/MS mRNA translation mRNA decay poly(A)-binding protein deadenylation translationally silenced and stabilized FMRP-mRNA complexes |
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