Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation

1. Download : Download high-res image (136KB)
2. Download : Download full-size image

     

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

1. Download : Download high-res image (267KB)
2. Download : Download full-size image

     

Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases

1. Download : Download high-res image (90KB)
2. Download : Download full-size image

     

An intronic GAA repeat expansion in FGF14 causes the autosomal-dominant adult-onset ataxia SCA50/ATX-FGF14

1. Download : Download high-res image (237KB)
2. Download : Download full-size image

     

Proximity labeling reveals non-centrosomal microtubule-organizing center components required for microtubule growth and localization

1. Download : Download high-res image (215KB)
2. Download : Download full-size image

     

A phospho-switch constrains BTL2-mediated phytocytokine signaling in plant immunity

1. Download : Download high-res image (202KB)
2. Download : Download full-size image

     

EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules

1. Download : Download high-res image (281KB)
2. Download : Download full-size image

     

Recombination of repeat elements generates somatic complexity in human genomes

1. Download : Download high-res image (446KB)
2. Download : Download full-size image

     

Human SMARCA5 is continuously required to maintain nucleosome spacing

1. Download : Download high-res image (146KB)
2. Download : Download full-size image

     

The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

1. Download : Download high-res image (200KB)
2. Download : Download full-size image

     

Modification of histidine repeat proteins by inorganic polyphosphate

1. Download : Download high-res image (186KB)
2. Download : Download full-size image

     

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins

1. Download : Download high-res image (174KB)
2. Download : Download full-size image

     

Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer

1. Download : Download high-res image (201KB)
2. Download : Download full-size image

     

Cooperative mechanics of PR65 scaffold underlies the allosteric regulation of the phosphatase PP2A

1. Download : Download high-res image (259KB)
2. Download : Download full-size image

     

Structure of Semliki Forest virus in complex with its receptor VLDLR

1. Download : Download high-res image (386KB)
2. Download : Download full-size image

     

The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs

1. Download : Download high-res image (233KB)
2. Download : Download full-size image

     

GCNA Preserves Genome Integrity and Fertility Across Species

1. Download : Download high-res image (170KB)
2. Download : Download full-size image

     

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins

1. Download : Download high-res image (190KB)
2. Download : Download full-size image

     

Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice

1. Download : Download high-res image (160KB)
2. Download : Download full-size image

     

Metabolic evolution in response to interspecific competition in a eukaryote

1. Download : Download high-res image (203KB)
2. Download : Download full-size image