共查询到20条相似文献,搜索用时 828 毫秒
1.
Juan Martinez Warren K. Laskey Cheri Wells Armin Foghi Sarah Rohde Mark Ricciardi Charlotte Mobarak 《Clinical proteomics》2010,6(3):65-73
Introduction
Radiographic contrast media (RCM) have numerous effects on the hemostatic system, inflammatory pathways, and vascular endothelium. Given the increasing number of high-risk patients undergoing radiographic procedures, more information regarding the systemic effects of RCM is needed. 相似文献2.
Manuel Fernández Martínez Jessica Castro Flores Susana Pérez de las Heras Aitziber Mandaluniz Lekumberri María Gordejuela Menocal Juan José Zarranz Imirizaldu 《BMC neurology》2008,8(1):39
Background
Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular risk factors (hypertension, diabetes mellitus and hypercholesterolemia) and depression has been evaluated. 相似文献3.
Background
Advanced glycation end-products (AGEs) and their receptor (RAGE) occur in dementia of the Alzheimer's type and diabetic microvascular disease. Accumulation of AGEs relates to risk factors for vascular dementia with ageing, including hypertension and diabetes. Cognitive dysfunction in vascular dementia may relate to microvascular disease resembling that in diabetes. We tested if, among people with cerebrovascular disease, (1) those with dementia have higher levels of neuronal and vascular AGEs and (2) if cognitive dysfunction depends on neuronal and/or vascular AGE levels. 相似文献4.
Miranda L Davies-Tuck Fahad Hanna Susan R Davis Robin J Bell Sonia L Davison Anita E Wluka Jenny Adams Flavia M Cicuttini 《Arthritis research & therapy》2009,11(6):R181-7
Introduction
Given the emerging evidence that osteoarthritis (OA) may have a vascular basis, the aim of this study was to determine whether serum lipids were associated with change in knee cartilage, presence of bone marrow lesions (BMLs) at baseline and the development of new BMLs over a 2-year period in a population of pain-free women in mid-life. 相似文献5.
Kayla D Viegas Sharul S Dol M Mehdi Salek Robert D Shepherd Robert M Martinuzzi Kristina D Rinker 《Biomedical engineering online》2011,10(1):20
Background
Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly prevalent pathogen capable of causing severe vascular infections. The goal of this work was to investigate the role of shear stress in early adhesion events. 相似文献6.
Pingxi Pan Hua Fu Lingjun Zhang He Huang Fengming Luo Wenchao Wu Yingqiang Guo Xiaojing Liu 《BMC cell biology》2010,11(1):36
Background
Atherosclerosis is now recognized as a chronic inflammatory disease. Angiotensin II (Ang II) is a critical factor in inflammatory responses, which promotes the pathogenesis of atherosclerosis. Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family cytokines and is associated with inflammatory progress of atherosclerosis. However, the potential link between PlGF and Ang II has not been investigated. In the current study, whether Ang II could regulate PlGF expression, and the effect of PlGF on cell proliferation, was investigated in human vascular endothelial cells (VECs) and smooth muscle cells (VSMCs). 相似文献7.
8.
Hyun-Mi Choi Yeon-Ah Lee Sang-Hoon Lee Seung-Jae Hong Dae-Hyun Hahm Sang-Yun Choi Hyung-In Yang Myung Chul Yoo Kyoung Soo Kim 《Arthritis research & therapy》2009,11(6):R161-10
Introduction
The role of adiponectin in the pathogenesis of arthritis is still controversial. This study was performed to examine whether adiponectin is involved in joint inflammation and destruction in rheumatoid arthritis (RA) in relation to the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs). 相似文献9.
Introduction
Cytochrome P450 epoxygenases metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs), which in turn are converted to dihydroxyeicosatrienoic acids (DHETs) by soluble epoxide hydrolase (sEH). EETs are known to modulate a number of vascular and renal functions, but the exact signaling mechanism(s) of these EET-mediated effects remains unknown. 相似文献10.
Background
Many in vitro studies have shown that adenosine (Ado) can induce vascular endothelial growth factor (VEGF) mRNA and protein expression and stimulate endothelial proliferation. In the present study, we seek to determine whether Ado can increase circulating levels of VEGF protein in the intact human. 相似文献11.
Ljiljana Vasović Milena Trandafilović Ivan Jovanović Aleksandra Antović Jovan Stojanović Miodrag Zdravković Miroslav Milić 《BMC neurology》2010,10(1):53
Background
As a continuation of the previous findings in human fetuses, accidental finding of an accessory vascular component in the posterior part of CAC of human adult cadavers inspired the authors to present and compare its posterior part configuration. 相似文献12.
Huey-Ming Lo Yih-Jeng Tsai Wen-Yuan Du Chih-Jen Tsou Wen-Bin Wu 《Journal of biomedical science》2012,19(1):18
Background
Platelet-derived growth factor (PDGF) is a potent stimulator of growth and motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor (PDGFR) are thought to contribute to vascular diseases and malignancy. We previously showed that a carotenoid, lycopene, can directly bind to PDGF and affect its related functions in VSMCs. In this study we examined the effect of the other naturally occurring carotenoid, lutein, on PDGF signaling and migration in VSMCs. 相似文献13.
Marlene Fischer Gregor Broessner Anelia Dietmann Ronny Beer Raimund Helbok Bettina Pfausler Andreas Chemelli Erich Schmutzhard Peter Lackner 《BMC neurology》2011,11(1):59
Background
Angiopoietin-1 (Ang-1) and -2 (Ang-2) are keyplayers in the regulation of endothelial homeostasis and vascular proliferation. Angiopoietins may play an important role in the pathophysiology of cerebral vasospasm (CVS). Ang-1 and Ang-2 have not been investigated in this regard so far. 相似文献14.
Shift from facilitative to neutral interactions by the cushion plant Silene acaulis along a primary succession gradient 下载免费PDF全文
Background
The stress‐gradient hypothesis predicts a shift from facilitative to competitive plant interactions with decreasing abiotic stress. This has been supported by studies along elevation and temperature gradients, but also challenged by the hypothesis of a facilitation collapse at extremely harsh sites. Although facilitation is known to be important in primary succession, few studies have examined these hypotheses along primary succession gradients.Aim
To examine whether there is a relationship between the presence of the circumpolar cushion plant Silene acaulis and other species, and if so, whether there is a shift between positive and negative interactions along a primary succession gradient in a glacier foreland.Location
Finse, southern Norway.Methods
We examined the performance of the common alpine forb Bistorta vivipara, species richness of vascular plants, bryophytes and lichens, and the number of seedlings and fertile vascular plants in S. acaulis cushions, and control plots without S. acaulis, along a succession gradient with increasing distance from a glacier front, and thus decreasing abiotic stress. To examine if S. acaulis cushions modify the abiotic environment, we recorded soil temperature, moisture, organic content and pH in cushions and control plots.Results
Bistorta vivipara performed better, as shown by bigger leaves in S. acaulis cushions compared to control plots in the harshest part of the gradient close to the glacier. There were few differences in B. vivipara performance between cushion and control plots in the more benign environment further away from the glacier. This suggests a shift from facilitative to mainly neutral interactions by S. acaulis on the performance of B. vivipara with decreasing abiotic stress. A trend, although not significant, of higher vascular species richness and fertility inside S. acaulis cushions along the whole gradient, suggests that S. acaulis also facilitates community‐level species richness. The causal mechanism of this facilitation is likely that the cushions buffer extreme temperatures.Conclusions
Our results support the stress‐gradient hypothesis for the relationship between the cushion plant S. acaulis and the performance of a single species along a primary succession gradient in a glacier foreland. S. acaulis also tended to increase vascular plant species richness and fertility regardless of stress level along the gradient, suggesting facilitation at the community level. We found no collapse of facilitation at the most stressful end of the gradient in this alpine glacier foreland. 相似文献15.
Automatic segmentation of coronary angiograms based on fuzzy inferring and probabilistic tracking 总被引:1,自引:0,他引:1
Background
Segmentation of the coronary angiogram is important in computer-assisted artery motion analysis or reconstruction of 3D vascular structures from a single-plan or biplane angiographic system. Developing fully automated and accurate vessel segmentation algorithms is highly challenging, especially when extracting vascular structures with large variations in image intensities and noise, as well as with variable cross-sections or vascular lesions. 相似文献16.
Hak Jin Kim Yong Woo Kim In Sook Lee Jong Woon Song Yeon Joo Jeong Seon Hee Choi Kyung Un Choi Kuen Tak Suh Byung Mann Cho 《Acta veterinaria Scandinavica》2009,51(1):30
Background
To test the hypothesis that triolein emulsion will increase vascular permeability of skeletal muscle. 相似文献17.
Chyi-Huey Bai Jiunn-Rong Chen Hou-Chang Chiu Chia-Chi Chou Lee-Young Chau Wen-Harn Pan 《Journal of biomedical science》2010,17(1):12
Background
The microsatellite polymorphism of heme oxygenase (HO)-1 gene promoter has been shown to be associated with the susceptibility to ischemic event, including coronary artery disease (CAD), myocardial infarction, and peripheral vascular disease. We aimed to examine whether the length of (GT)n repeats in HO-1 gene promoter is associated with ischemic stroke in people with CAD risk factors, especially low level of HDL. 相似文献18.
Bàrbara Segura María Ángeles Jurado Núria Freixenet Núria Bargalló Carme Junqué Adrià Arboix 《BMC neurology》2010,10(1):64
Background
Metabolic Syndrome (MetSd) is a cluster of vascular risk factors that may influence cerebrovascular pathology during aging. Recently, microstructural white matter (WM) changes detected by diffusion tensor imaging (DTI) and processing speed deficits have been reported in MetSd patients. We aimed to test the relationship between WM alteration and cognitive impairment in these patients. 相似文献19.
Background
Reactive oxygen species (ROS) were shown to mediate aberrant contractility in hypertension, yet the physiological roles of ROS in vascular smooth muscle contraction have remained elusive. This study aimed to examine whether ROS regulate α1-adrenoceptor-activated contraction by altering myosin phosphatase activities. 相似文献20.