广东丰顺地区老年高血压患者的危险因素及合并症的特征

目的:分析广东省丰顺地区老年高血压患者的临床特点,为临床治疗该地区老年高血压病提供参考。方法:选取广东省丰顺县人民医院等共3所医院2015年1月至2016年1月收治的老年高血压患者827例,并对所收集的临床资料进行整理,回顾性分析该地区老年人高血压病心脑血管危险因素的分布特征以及其合并症的发生情况。结果:本次纳入研究的827例老年高血压患者中,男性409人,占49.5%,女性418人,占50.5%,平均年龄(75.32±8.74)岁。其中,34.23%存在血脂异常,15.60%有吸烟史,4.47%有高血压家族史,肥胖占2.06%,23.10%合并糖尿病,29.02%合并冠心病,5.20%合并心力衰竭,28.78%合并脑血管疾病,25.83%合并肾功能不全。不同高血压级别合并脑血管病、冠心病、心力衰竭、肾功能不全的发生率存在显著差异(P=0.047,P0.001,P=0.026,P=0.041),而吸烟、血脂异常、肥胖、糖尿病的占比差异无统计学意义(P0.05)。结论:广东省丰顺地区老年高血压患者在心脑血管病危险因素中所占比重最大的是血脂异常,合并冠心病及脑血管疾病比例最大,这可能与血脂异常有着密切的关系。     

住院糖尿病患者中甲状腺结节的流行病学研究

目的:观察住院糖尿病患者中甲状腺结节的患病率,探讨二者间潜在的关系。方法:于2008年8月~2011年12月间对上海交通大学附属第一人民医院南院因糖尿病收治入院的全部患者进行甲状腺相关病史收集、血清甲状腺激素检测及超声波检查,以筛查甲状腺结节。结果:在收治的660例糖尿病患者中,住院期间发现并诊断合并有甲状腺结节患者为221例,患病率为33.5%。进一步分析糖尿病患者临床特征与甲状腺结节关系,男性为29.8%,女性为38.4%,明显高于男性患者,二者相比差异有统计学意义(P<0.05);糖尿病患者甲状腺结节患病率有随年龄增长而升高的趋势,与≤30岁年龄组相比,年龄51岁~70岁组及≥70岁组结节患病率均明显升高,差异有统计学意义(41.1%,37.6%15.4%,均P<0.05);1型糖尿病患者甲状腺结节患病率为24.1%,2型糖尿病中为35.3%,高于1型糖尿病,差异有统计学意义(P<0.05);糖尿病患者中,不同体重指数、病程、治疗方法组中甲状腺结节患病率相互比较均无明显差异性(均P>0.05)。结论:住院糖尿病患者中甲状腺结节患病率较高,尤其是女性、较大年龄及2型糖尿病患者更为突出,临床上有必要对这些患者进行甲状腺结节的筛查。     

女性冠心病患者的危险因素分析及与冠脉病变严重程度的关系

目的:了解女性冠心病患者的危险因素及与冠脉病变严重程度的关系。方法:随机选取本院2012年至2014年心血管科住院治疗的疑似冠心病女性患者150例,经冠脉造影确诊冠心病患者105例,非冠心病患者45例。对患者的临床资料和冠脉病变严重程度进行单因素和多因素分析。结果:冠心病患者高血压与糖尿病百分比、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)及纤维蛋白原水平均高于非冠心病患者,而高密度脂蛋白(HDL-C)和血红蛋白水平均低于非冠心病患者(P0.05);年龄、高血压与糖尿病百分比、血脂上升百分比(高TC、高TG、低HDL-C、高LDL-C)、高尿酸百分比和纤维蛋白原水平均随冠状动脉病变支数及Gensini积分的增加而增加(P0.05);多因素分析发现女性冠心病的影响因素分别为高LDL-C、糖尿病、低HDL-C、TG和高血压,其中高LDL-C的影响最为显著(P0.05)。结论:高血压、糖尿病史、血脂水平为女性冠心病的影响因素,其中高LDL-C的影响最显著,各影响因素均与冠脉病变程度紧密相关。     

高血压流行病学病因分析和总结

近年来,由于社会变革和人们生活方式的变化,我国心血管病发病率及相关危险因素均有增加趋势。据2002年卫生部组织的全国居民27万人营养与健康状况调查资料显示,我国居民膳食质量明显提高,但城市居民膳食结构不尽合理。畜肉类及油脂类消费过多,慢性非传染性疾病患病率上升迅速(2)。我国18岁及以上居民高血压患病率为18.8%,估计全国患病人数1.6亿多。与1991年比较,患病率上升31%。我国人群高血压知晓率为30.2%,治疗率为24.7%,控制率为6.1%,与1991年比有所提高,但仍处于较差水平。高盐饮食与高血压患病密切相关,饮酒与高血压和血脂异常的患病密切相关,脂肪摄入多且体力活动少的人,患高血压病的机会多。     

糖尿病患者血脂检测的临床价值

目的研究分析糖尿病患者血脂异常的因素,以达到有效治疗糖尿病及其并发症的目的。方法通过随机分组法将我院2012年3月~2013年10月收治的108例糖尿病患者作为观察组,同时选择健康体检者180例作为对照组。两组均在清晨时行空腹抽血检测血清中的甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、总胆固醇(TC),并对两组数据进行分析比较。结果 108例糖尿病患者血清中TC、TG以及LDL-C含量明显高于对照组,差异具有统计学意义(P0.05);但两组患者血清HDL-C含量无统计学意义(P0.05)。糖尿病患者血脂异常发生率为57.41%,健康体检者血脂异常发生率为8.64%,两组比较具有统计学意义(P0.05)。结论糖尿病患者容易出现血脂异常,对糖尿病患者应及时检测血脂情况,这对防范糖尿病及其它并发症的发生具有重要意义。     

冠心病合并高血压患者左室质量指数与冠脉病变严重程度的相关性分析

目的:探讨冠心病合并高血压患者左室质量指数(LVMI)与冠脉病变严重程度的相关性。方法:选取在我院住院的冠心病合并高血压患者168例为研究对象,所有患者入院后均行心脏超声检查,按照LVMI水平的中位数将患者分为A组(LVMI≥115.71g/m~2,n=82例)和B组(LVMI115.71g/m~2,n=86例);比较两组的实验室检查指标与冠脉病变支数及Gensini积分差异。利用多元线性回归方程分析影响Gensini积分的相关因素。结果:与B组比较,A组患者收缩压(SBP)、甘油三酯(TG)、B型脑钠肽(BNP)、血清肌酐(Scr)较高(P0.05);A组中Gensini积分亦高于B组(P0.05),三支病变的比例高于B组(P0.05);Gensini积分高分组LVMI高于中分组及低分组(P0.05),中分组高于低分组(P0.05);Pearson相关性分析显示:Gensini积分与LVMI呈现正相关(P0.05),亦与SBP、TG、Scr、BNP呈正相关(P0.05);多元线性回归分析显示:LVMI是Gensini积分增高的独立危险因素(P0.05)。结论:冠心病合并高血压患者LVMI增高与冠脉病变严重程度具有一定正相关性,可能是影响患者冠脉病变严重程度的独立危险因素。     

不同驻地海军官兵足癣近3年流行病学调查分析

目的分析不同驻地海军官兵足癣近3a患病率、临床分型和致病菌种的分布情况。方法分别于2013、2014、2015年在4个海军驻地:北京、大连、宁波、三亚,随机选取600名官兵,对其足癣患病率、致病菌菌种及临床类型进行调查。结果 4个驻地海军官兵足癣的患病率仅在2013年具有统计学意义(P0.05),其中三亚驻地患病率为18.0%,高于其他3处;近3a北京、大连足癣患病率呈升高趋势(P0.05)。各驻地足癣致病菌菌种分布均以红色毛癣菌为主,须癣毛癣菌、犬小孢子菌、白念珠菌、絮状表皮癣菌其次。三亚、宁波驻地红色毛癣菌检出率70.1%、70.9%,高于北京、大连驻地的62.8%、56.5%(P0.05),而须癣毛癣菌检出率分别为12.9%、16.1%,低于北京、大连驻地的26.4%、26.3%(P0.05),絮状表皮癣菌检出率在三亚最高(P0.05),为1.9%。4个驻地官兵中水疱鳞屑型足癣患者构成比差异无统计学意义,三亚驻地浸渍糜烂型患者构成比为23.0%,高于其他3处(P0.05),而角化过度型患者构成比为20.3%,低于其他3处(P0.05)。结论北京、大连近3a足癣患病率呈升高趋势,4个驻地海军官兵足癣致病菌、临床类型有明显的差异。     

高血压合并糖尿病临床治疗体会

目的探讨高血压合并糖尿病患者的有效治疗措施。方法选择2013年6月~2015年1月我院接诊的150例高血压合并糖尿病患者作为研究对象,采用数字表法将患者随机分为A、B、C组各50例。A组采用血管紧张素转换酶抑制剂联合小剂量利尿治疗,B组采用钙拮抗剂治疗,C组采用β受体阻滞剂治疗,并观察3组患者的治疗效果。结果A组治疗总有效率为94.0%,显著高于B、C组(分别为80.0%、78.0%),差异具有显著统计学意义(均P0.05);3组患者治疗后均出现不同程度的药物不良反应,B、C组的不良反应发生率分别为16.0%、18.0%,均显著高于A组的6.0%,组间比较差异具有显著统计学意义(P0.05)。结论高血压合并糖尿病患者采取联合用药的方案可更好的控制血压及血糖水平,有效降低药物不良反应,值得临床推广应用。     

超声对评估老年颈动脉粥样硬化与退行性心脏瓣膜病的价值

目的:研究超声在评估老年颈动脉粥样硬化与退行性心脏瓣膜病关系中的应用价值。方法:选择2013年1月~2015年12月在我院进行诊治的52例退行性心脏瓣膜病老年患者为观察组,52例非退行性心脏瓣膜病老年患者作为对照组。行超声检查后,观察患者的颈动脉斑块积分(Crouse积分)和颈动脉内膜中层厚度(IMT),比较两组患者的心脏管腔狭窄和管腔堵塞情况,以及两组高血压、冠状动脉粥样硬化性心脏病和糖尿病的发生情况。结果:观察组52例退行性心脏瓣膜病老年患者中,心脏瓣膜钙化程度分级为1级的有18例,2级有19例,3级有15例。心脏瓣膜钙化程度分级为3级的患者Crouse积分和IMT均明显高于1级和2级(P0.05),且2级明显高于1级(P0.05);观察组心脏管腔堵塞和狭窄的发生率均明显高于对照组(P0.05);观察组高血压、冠心病和糖尿病的发生率均明显高于对照组(P0.05)。结论:老年颈动脉粥样硬化与退行性心脏瓣膜病紧密相关,利用超声检查能对老年颈动脉粥样硬化和退行性心脏瓣膜病的病情进行有效评估。     

合肥市某区15岁以上人群高血压影响因素调查

目的：了解合肥市包河区高血压罹患现状,分析影响高血压的相关膳食因素以及体力活动因素,提出针对性干预措施,为更好地开展预防高血压为主的预防保健服务提供基础依据,减少高血压相关疾病的发生。方法：选择在2014 年 6月～2014 年12 月合肥市包河区的1 899名15岁以上常住人口作为研究对象,利用回顾性调查的方式获取详尽的记录。采用 t 检验、χ2检验、Logistic 回归进行统计分析,统计学显著性水准α取 0.05。结果：本次调查中,共调查1 899人,年龄47.14±17.87岁,男性956人、女性943人,高血压患病率27.96%（男31.38%、女24.50%）。统计检验结果显示,与非高血压组相比,高血压组年龄、BMI、腰围、基础代谢、身体脂肪率、内脏脂肪指数均较大（P＜0.05）。每周3次及以上的高强度的工作、高强度的休闲活动、步行或骑自行车与高血压患病率呈负相关（P＜0.05）。高血压组的睡眠时间少于非高血压组（P＜0.05）。结论：较大强度的体力活动、充足而又良好的休息、适宜的体重可以有效降低高血压的发生。     

Secular decline in mortality from coronary heart disease in adults with diabetes mellitus: cohort study

Objective To examine trends in fatal coronary heart disease in adults with and without diabetes.Design Cohort study.Setting Two surveys of the Nord-Trøndelag health study (HUNT), a population based study in Norway.Participants 74 914 men and women from the first survey (1984-6) and 64 829 from the second survey (1995-7).Main outcome measure Age specific mortality from coronary heart disease among adults with and without diabetes during two consecutive nine year follow-up periods.Results A total of 2623 men and 1583 women died from coronary heart disease. Mortality rates were substantially lower during the most recent follow-up period: among men aged 70-79 without diabetes, deaths per 1000 person years declined from 16.38 to 8.79 (reduction 48%, 95% confidence interval 39% to 55%) and among women aged 70-79 from 6.84 to 2.68 (62%, 52% to 70%). Among the same age group with diabetes, deaths per 1000 person years in men declined from 38.97 to 17.89 (54%, 32% to 69%) and in women from 28.15 to 11.83 (59%, 37% to 73%). The reduction was more noticeable in age groups younger than 70 at baseline, and less pronounced among people aged 80 or more. Mortality from coronary heart disease was more than twofold higher in people with than without diabetes, with a slightly stronger association in women. The difference in mortality by diabetes status remained almost unchanged from the first to the second survey.Conclusion The strong general reduction in mortality rates from coronary heart disease from the first to the second follow-up period also benefited people with diabetes, but the more than twofold higher mortality from coronary heart disease associated with diabetes persisted over time.     

Educational status,coronary heart disease,and coronary risk factor prevalence in a rural population of India.

OBJECTIVE--To define the association between educational level and prevalence of coronary heart disease and coronary risk factors in India. DESIGN--Total community cross sectional survey with a doctor administered questionnaire, physical examination, and electrocardiography. SETTING--A cluster of three villages in rural Rajasthan, western India. SUBJECTS--3148 residents aged over 20 (1982 men, 1166 women) divided into various groups according to years of formal schooling. RESULTS--Illiteracy and low educational levels were associated with less prestigious occupations (agricultural and farm labouring) and inferior housing. There was an inverse correlation of educational level with age (rank correlation: mean -0.45, women -0.49). The prevalence of coronary heart disease (diagnosed by electrocardiography) was significantly higher among uneducated and less educated people and showed an inverse relation with education in both sexes. Among uneducated and less educated people there was a higher prevalence of the coronary risk factors smoking and hypertension. Educational level showed a significant inverse correlation with systolic and diastolic blood pressure. Logistic regression analysis with adjustment for age showed that educational level had an inverse relation with prevalence of electrocardiographically diagnosed coronary heart disease (odds ratio: men 0.82, women 0.53), hypertension (men 0.88, women 0.56), and smoking (men 0.73, women 0.65) but not with hypercholesterolaemia and obesity. The inverse relation of coronary heart disease with educational level abated after adjustment for smoking, physical activity, body mass index, and blood pressure (odds ratio: men 0.98, women 0.78). CONCLUSION--Uneducated and less educated people in rural India have a higher prevalence of coronary heart disease and of the coronary risk factors smoking and hypertension.     

老年高血压患者踝肱指数及其与冠心病、脑卒中相关性的研究

目的:了解老年高血压患者外周动脉性疾病(PAD)患病率及其特点,重点研究踝肱指数(ABI)与冠心病、脑卒中相关性的临床意义.方法:入选我院和安贞医院门诊及住院老年男性高血压患者,无损伤周围血管检查仪测定患者踝肱指数、标准问卷调查及各项指标测量确定患者身体基线状况;任一侧肢体ABI≤0.9诊断为PAD,1.01-1.30...     

血清胆红素、NO、ET-1、VEGF水平联合检测对冠心病诊断价值

摘要 目的：探讨血清胆红素、一氧化氮（NO）、内皮素-1（ET-1）、血管内皮生长因子（VEGF）水平联合检测对冠心病（CHD）的诊断价值。方法：选取2019年12月至2020年12月在我院治疗的冠心病患者65例作为观察组;另选取同期参与健康体检的60例健康人群作为对照组。对所有患者总胆红素水平（TBIL）、直接胆红素水平（DBIL）、NO、ET-1、VEGF表达水平进行检测,计算间接胆红素水平（IBIL）,采用受试者工作特征曲线（ROC）下面积（AUC）比较血清胆红素、VEGF、ET-1和NO单独和联合检测对冠心病的诊断价值,采用单因素和多因素logistic回归分析法分析冠心病的影响因素。结果：与对照组相比,观察组患者血清IBIL、DBIL、TBIL、VEGF和NO检测结果均显著降低,ET-1检测结果显著升高（P＜0.05）。血清胆红素、VEGF、ET-1和NO对冠心病联合检测的AUC值显著高于单独检测值（P＜0.05）。观察组患者高血压、糖尿病、血脂异常、吸烟、肥胖的发生率明显高于对照组（P＜0.05）。多因素非条件logistic回归分析结果显示,高血压、糖尿病、血脂异常、吸烟、肥胖、血清胆红素、VEGF、ET-1和NO均可作为评估冠心病的危险因素,其中血清检测指标的关联强度依次为ET-1、VEGF、NO、胆红素（P＜0.05）。结论：冠心病患者血清胆红素代谢异常,血管内皮功能指标紊乱,是导致患者动脉粥样硬化的重要原因。血清胆红素、NO、ET-1、VEGF水平联合检测对冠心病诊断效能明显优于单个指标,且可作为冠心病发病风险的有效指标。     

Sex-Specific Prevalence of Diabetes and Cardiovascular Risk Factors in the Middle-Aged Population of China: A Subgroup Analysis of the 2007–2008 China National Diabetes and Metabolic Disorders Study

The sex difference in the prevalence rates of diabetes and cardiovascular diseases (CVDs) among the middle-aged population in China remain largely unknown. Therefore, we analyzed differences in the prevalence of diabetes, self-reported CVDs, and some CVD risk factors among men and women in the middle-aged population (30–49 years) and in individuals aged 50 years and older using data from the China National Diabetes and Metabolic Disorders Study of 2007–2008. Middle-aged men appeared to have significantly a higher prevalence of diabetes and self-reported CVDs than middle-aged women (8.07% vs 5.06% for diabetes, P < 0.001; 0.64% vs 0.22% for CVDs, P < 0.001). Men also showed higher rates of central obesity, hypertension, and dyslipidemia than women (all P < 0.01). Compared with women, men were more likely to drink alcohol and smoke cigarettes but less likely to be under diet control. The sex-specific differences in prediabetes, CVD, and CVD risk factors between men and women were diminished or even reversed in the population aged 50 years and older. No sex-specific differences were found in the prevalences of a family history of diabetes, coronary heart disease, and hypertension (P > 0.05) in middle-aged population. Specific strategies to reduce modifiable risk factors for the prevention and control of diabetes and CVD may be warranted in this population.     

Quality of cardiovascular disease care in Ontario, Canada: missed opportunities for prevention - a cross sectional study

ABSTRACT: BACKGROUND: Primary care plays a key role in the prevention and management of cardiovascular disease (CVD). We examined primary care practice adherence to recommended care guidelines associated with the prevention and management of CVD for high risk patients. METHODS: We conducted a secondary analysis of cross-sectional baseline data collected from 84 primary care practices participating in a large quality improvement initiative in Eastern Ontario from 2008 to 2010. We collected medical chart data from 4,931 patients who either had, or were at high risk of developing CVD to study adherence rates to recommended guidelines for CVD care and to examine the proportion of patients at target for clinical markers such as blood pressure, lipid levels and hemoglobin A1c. RESULTS: Adherence to preventive care recommendations was poor. Less than 10% of high risk patients received a waistline measurement, half of the smokers received cessation advice, and 7.7% were referred to a smoking cessation program. Gaps in care exist for diabetes and kidney disease as 54.9% of patients with diabetes received recommended hemoglobin-A1c screenings, and only 55.8% received an albumin excretion test. Adherence rates to recommended guidelines for coronary artery disease, hypertension, and dyslipidemia were high (>75%); however <50% of patients were at target for blood pressure or LDL-cholesterol levels (37.1% and 49.7% respectively), and only 59.3% of patients with diabetes were at target for hemoglobin-A1c. CONCLUSIONS: There remain significant opportunities for primary care providers to engage high risk patients in prevention activities such as weight management and smoking cessation. Despite high adherence rates for hypertension, dyslipidemia, and coronary artery disease, a significant proportion of patients failed to meet treatment targets, highlighting the complexity of caring for people with multiple chronic conditions.Trial RegistrationNCT00574808.     

比较老年与中青年二尖瓣腱索断裂的超声心动图特征和规律性

目的：比较老年二尖瓣腱索断裂（RMCT）患者与中青年RMCT患者的临床表现以及超声心动图特点,为老年RMCT患者的诊断和治疗提供依据。方法：选择年龄〉60岁的老年RMCT患者53例定义为老年组,年龄〈60岁的中青年RMCT患者57例定义为中青年组,使用经胸超声心动图（TTE）和经食道超声心动图（TEE）测量各组的心腔尺寸,观察二尖瓣活动形态以及腱索断裂的部位和程度,记录瓣膜的返流情况。结果：老年组中风心病仅占5．66％,而中青年组风心病患者占50．88％,差异有统计学意义（X2=27．221,P=0．000）。老年组多合并有多种慢性疾病,其中合并高血压者占83．02％,合并冠心病者占60．38％,合并2型糖尿病者占37．74％,均高于中青年组,其中合并高血压的差异有统计学意义（X2=-31．459,P=0．000）。老年组中心功能Ⅳ级的比例远高于中青年组,差异有统计学意义（X2=10．489,P=0．001）。老年组全心扩大、肺动脉高压的例数显著高于中青年组,差异有统计学意义（全心扩大：XZ=11．376,P=0．001;肺动脉高压：X2=-20．362,P=0．000）。老年组中二尖瓣细小腱索断裂的例数多于中青年组,差异有统计学意义（x2=9．799,P=0．002）,粗大腱索断裂的例数少于中青年组,差异有统计学意义（x2=11．118,P=0．001）。结论：合并有高血压、冠心病以及糖尿病等基础疾病的老年RMCT患者,应定期进行超声心动图的检查,同时给予合理的治疗,以降低心衰的发病率。     

High Prevalence and Associated Risk Factors for Impaired Renal Function and Urinary Abnormalities in a Rural Adult Population from Southern China

Background

The prevalence of chronic kidney disease (CKD) has increased and will continue to rise worldwide. However, data regarding the prevalence of CKD in a rural area of China are limited. We therefore investigated the prevalence and associated risk factors of impaired renal function and urinary abnormalities in an adult rural population in southern China.

Methods

Between December 2006 and January 2007, residents older than 20 years from four villages in Zhuhai city were randomly selected using a stratified, multistage sampling technique. All participants were interviewed and tested for hematuria, albuminuria and estimated glomerular filtration rate (eGFR). The associations between age, gender, diabetes mellitus, hypertension, hyperuricemia, education level and indicators of renal damage were examined.

Results

Overall, 1,214 subjects were enrolled in this study. After adjustment for age and gender, the prevalence of albuminuria was 7.1% (95% CI: 4.5, 8.1), reduced eGFR was 2.6% (95% CI: 1.7%, 3.3%), and hematuria was 4.6% (95% CI: 3.3%, 6.0%). Approximately 13.6% (95% CI: 12.0%, 15.1%) of the patients had at least one indicator of renal damage, but only 8.3% were previously aware. Age, diabetes, hyperlipidemia, hypertension, hyperuricemia, use of nephrotoxic medications, coronary heart disease and history of CKD were independently associated with impaired renal function and urinary abnormalities. Additionally, age, diabetes, and hypertension were independently associated with albuminuria. Age, hypertension, hyperuricemia, central obesity, and coronary heart disease were independently associated with reduced renal function.

Conclusions

The high prevalence and low awareness of impaired renal function and urinary abnormalities in this population illustrates the urgent need to implement a CKD prevention program in the rural areas of southern China.     

Association between Psoriasis Vulgaris and Coronary Heart Disease in a Hospital-Based Population in Japan

BackgroundPsoriasis vulgaris is a chronic inflammatory skin disease with an immune-genetic background. It has been reported as an independent risk factor for coronary heart disease (CHD) in the United States and Europe. The purpose of this study was to investigate the association between psoriasis and CHD in a hospital-based population in Japan.MethodsFor 113,065 in-hospital and clinic patients at our institution between January 1, 2011 and January 1, 2013, the diagnostic International Classification of Diseases (ICD)-10 codes for CHD, hypertension, dyslipidemia, diabetes, and psoriasis vulgaris were extracted using the medical accounting system and electronic medical record, and were analyzed.ResultsThe prevalence of CHD (n = 5,167, 4.5%), hypertension (n = 16,476, 14.5%), dyslipidemia (n = 9,236, 8.1%), diabetes mellitus (n = 11,555, 10.2%), and psoriasis vulgaris (n = 1,197, 1.1%) were identified. The prevalence of CHD in patients with hypertension, dyslipidemia, diabetes, and psoriasis vulgaris were 21.3%, 22.2%, 21.1%, and 9.0%, respectively. In 1,197 psoriasis patients, those with CHD were older, more likely to be male, and had more number of the diseases surveyed by ICD-10 codes. Multivariate analysis showed that psoriasis vulgaris was an independent associated factor for CHD (adjusted odds ratio [OR]: 1.27; 95% confidence interval [CI]: 1.01–1.58; p = 0.0404) along with hypertension (adjusted OR: 7.78; 95% CI: 7.25–8.36; p < 0.0001), dyslipidemia (adjusted OR: 2.35; 95% CI: 2.19–2.52; p < 0.0001), and diabetes (adjusted OR: 2.86; 95% CI: 2.67–3.06; p < 0.0001).ConclusionPsoriasis vulgaris was independently associated with CHD in a hospital-based population in Japan.