共查询到20条相似文献,搜索用时 46 毫秒
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P S Henthorn M Raducha T Kadesch M J Weiss H Harris 《The Journal of biological chemistry》1988,263(24):12011-12019
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Structure of the human liver/bone/kidney alkaline phosphatase gene 总被引:23,自引:0,他引:23
M J Weiss K Ray P S Henthorn B Lamb T Kadesch H Harris 《The Journal of biological chemistry》1988,263(24):12002-12010
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Characterization of a 5'-flanking region of the human liver/bone/kidney alkaline phosphatase gene: two kinds of mRNA from a single gene 总被引:2,自引:0,他引:2
S Matsuura F Kishi T Kajii 《Biochemical and biophysical research communications》1990,168(3):993-1000
We have cloned the human liver/bone/kidney alkaline phosphatase (ALPL) gene using a liver-type ALPL cDNA as a probe. The gene is divided into 12 exons, and is likely to exist as a single copy in haploid genome. As compared with the gene isolated using a bone-type ALPL cDNA (Weiss et al., J. Biol. Chem. 263, 12002-12010, 1988), another leader exon specific for the liver-type ALPL mRNA was assigned about 3.4 kb upstream from exon 2 and the alternative splicing in the first exon was indicated. RNA blot analysis showed that three species of mRNA of 2.5, 4.1 and 4.7 kilobases were detected in liver and developmentally regulated. 相似文献
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Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase 总被引:24,自引:0,他引:24
J M Ntambi S A Buhrow K H Kaestner R J Christy E Sibley T J Kelly M D Lane 《The Journal of biological chemistry》1988,263(33):17291-17300
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