学龄双生子儿童身体围度与宽度指标的遗传学分析

为探讨遗传和环境因素对学龄双生子儿童身体围度及宽度等体格指标的影响,对351对6~12岁双生子儿童身高、胸围、腰围、臀围、肩宽、骨盆宽指标进行测量,计算各指标的相关指数。应用Mx软件拟合最佳结构方程模型计算各指标遗传度,分析年龄与性别的作用。结果发现,各指标拟合的最佳模型均为ACES,各测量指标的年龄方差较大(0.21~0.76),衍生指数中除腰臀比(女0.15,男0.05)外几乎均不存在年龄方差;各指标的共同环境方差变异较大(0.00~0.53);衍生指数的特殊环境因素方差(0.09~0.25)总体上高于测量指标(0.01~0.09)。校正年龄后,各指标遗传度为身高(女63%,男59%)、胸围(女84%,男88%)、身高胸围指数(女87%,男55%)、腰围(女46%,男64%)、臀围(女61%,男61%)、腰臀比(女44%,男44%)、肩宽(女78%,男78%)、骨盆宽(女62%,男62%)、身高肩宽指数(女40%,男40%)、身高骨盆宽指数(女35%,男48%)、肩宽骨盆宽指数(女24%,男24%)。结果表明学龄双生子儿童身高、胸围、身高胸围指数、臀围、肩宽、骨盆宽主要受遗传因素影响;腰臀比、身高肩宽指数、身高骨盆宽指数及肩宽骨盆宽指数受环境因素影响更大;遗传与环境因素对身高胸围指数、腰围指标的影响可能存在一定性别差异;年龄对学龄双生子儿童身体围度及宽度相关指数的影响较小。     

中国不同地理分区人群的头面部特征

本文对近年来测量的45254例（男19892例，女25362例）中国人的18项头面部测量数据，按地理分区进行统计与主成分分析，发现中国东北、华北人群男性耳较长，两眼外角距离较近、鼻较狭，头、面较宽；华南人群耳较短，眼、鼻较宽，头较狭，面较狭；东北、华北人群女性面较高，面较宽，两眼距离较大，耳较长；华南、西南人群女性面较低，面较狭，两眼距离较近，耳较短。对中国人群和外国人群头面部数据进行主成分分析和聚类分析，发现中国人群男性、女性头面部特征都相对接近于高加索人种的波斯人、北美白人，与尼格罗人种的非裔美国人差距较大，与南亚人差距也较大；中国男性容貌耳长，眼内角间宽、鼻宽、头宽、形态面高值多小于尼格罗人种的4个人群，形态面高值多小于高加索人种的波斯人；中国女性鼻宽、口宽值小于非裔美国人，容貌面高、眼内角间宽、面宽多大于北美白人、伊朗人。中国地理分区人群头面部特征的共性与人群间长期的融合、具有相似的遗传结构有关，环境因素是其存在差异的重要原因。     

江西汉族人头面部形态特征的年龄变化

为研究人类头面部形态特征随年龄增长而变化的规律, 赴江西省丰城调查了汉族705例(城男151, 城女156, 乡男203, 乡女195)38项头面部指标, 并计算了12项头面部体质指数, 对江西汉族头面部形态特征的年龄变化进行了初步分析。结果显示: 江西汉族人头面部形态特征随年龄增长呈现一定的变化规律。1)随年龄增长, 江西汉族成人有蒙古褶率下降, 眼裂倾斜度渐趋水平, 眼色变浅, 上唇皮肤部高度狭窄型率下降, 红唇厚度窄型率上升。2)相关分析显示, 江西汉族鼻宽、口裂宽、鼻深、上唇皮肤部高度、容貌耳长、容貌耳宽与年龄呈正相关; 眼外角间宽、唇高、红唇厚度与年龄呈负相关; 3)江西汉族人头长宽指数、口指数与年龄呈负相关。4)方差分析显示, 上述指标值、指数值在不同年龄组间差异均具有统计学意义。     

腊尔山区苗族学生头面部形态特征

本项目对1896例腊尔山区6~16岁苗族学生（男919例,女977例）进行了人体测量,测量了10项头面部形态指标,并根据公式计算13项头面部指数值。结果表明,苗族学生头面部各指标均值随年龄增长而增加,同年龄段头面部各指标均值男生一般高于女生,且多数年龄段差异有统计学意义;男性的头长宽的、形态面的、形态上面的、容貌面的、颧额宽的、容貌上面的和容貌上面高的指数以及女性的形态面的、形态上面的、容貌面的、颧下颌宽度的、容貌上面高的指数随年龄增长总体趋势是先增加后递减;男性头面高的以及女性的头长高的、头宽高的和头面宽的指数随年龄增长逐渐增加;男女性之间的头长高的、头宽高的和额顶宽的指数比较显示,多数年龄段差异有统计学意义;苗族学生头型以中头型、高头型、阔头型多见,面型以阔面型、阔上面型为主;相对于其他族群,腊尔山苗族男生面型短而宽,头型偏长,女生面型偏短,头型稍偏长而窄。腊尔山苗族学生头面部特征与融水苗族、土家族等族群较为接近,与哈萨克族、新乡汉族相距较远。     

凹耳蛙的两性异形

测量和比较采自黄山的凹耳蛙成体标本(雌雄各20个),统计结果表明成年雌雄蛙的体长、头宽、吻长、鼻间距、眼间距、眼径、鼓膜宽、前臂及指长、前臂宽等两性形态学指标存在显著性差异。对与体长显著相关的形态特征,以体长为协变量的协方差分析表明凹耳蛙雌雄两性在头宽、眼间距、眼径、鼓膜宽存在显著差异。凹耳蛙两性异形比达到0.418,雌性平均体长对雄性平均体长的比达到1.716。头宽、眼间距、眼径、鼓膜宽等局部形态特征与体长的线性回归分析表明,雌性斜率大于雄性斜率,说明雌性凹耳蛙上述局部特征随体长的生长速率明显大于雄性。雌性体长的繁殖力选择能够很好地解释凹耳蛙的两性异形。     

青少年双生子体型指征相关指标的遗传度研究(英文)

目的:用经典的双生子设计探讨遗传因素对青少年身高、体重、体质指数(BMI)等体型指征的影响程度。方法:从青岛市双生子库中选择自愿参加本研究的362对11-19岁双生子,测量身高、体重。同性别的双生子通过16个多态标记进行卵型鉴定,在此基础上,应用Mx软件构建结构方程模型分析计算遗传度。结果:对362对有效双生子数据进行分析,其中同卵双生子194对,异卵双生子168对,身高的最佳拟合模型ACE模型,体重和BMI的最佳拟合模型为AE模型。调整年龄性别后,身高的遗传度为66%,体重的遗传度为84%,体质指数的遗传度为75%。结论:在青少年体型指征的相关指标中,身高、体重、BMI受遗传因素影响都较大。     

中国14个特殊旁系族群的头面部特征比较

头面部特征是人类学各人种进行分类的重要依据,在人类学的研究中被用作亲缘关系的证据。2006-2016年在四川、云南、西藏、贵州、海南、新疆、内蒙古共调查14个族群成人2989人（男性1434人,女性1555人）的16项头面部指标,比较这些族群头面部特征差异。研究结果如下：1）在男性族群中木雅人、尔苏人、临高人、白马人的面宽、头宽均较大。图瓦人、布里亚特人、摩梭人的面宽、头宽、形态面高、鼻高值均较大。僜人、革家人、莽人的面宽、头宽较小,而形态面高、鼻高值较大。空格人的面宽、头宽、形态面高、鼻高值均较小。2）在女性族群中图瓦人、布里亚特人的头宽、面宽、鼻高、耳上头高均较大。革家人、空格人的头宽、面宽、鼻高、耳上头高均较小。木雅人、尔苏人、八甲人、白马人、夏尔巴人的头宽、面宽较大,鼻高、耳上头高较小。僜人、克木人、莽人的头宽、面宽较小,而鼻高、耳上头高较大。3）头宽、容貌耳长跟纬度、年平均气温、年降雨量等环境因子相关性较高。4）通过聚类分析和主成分分析木雅人、尔苏人、白马人与羌族头面部特征比较接近。克木人与佤族头面部特征最为接近。革家人、僜人、莽人头面部特征比较接近。图瓦人、布里亚特人头面部特征与蒙古族比较接近。     

遗传和环境因素对儿童青少年身体高度及其比例的影响

目前有关儿童青少年坐高、下肢长及其比值的报道多为非双生子人群的研究。为了解遗传和环境因素对儿童青少年坐高、下肢长及坐高与下肢长比值影响的相对大小,我们对796对6~18岁双生子的身高和坐高进行了测量,计算下肢长及坐高与下肢长比值,采用结构方程模型分析其遗传和环境相对效应。结果发现,校正年龄后,男女15~18岁年龄组坐高和下肢长的遗传度（0.63~0.78）均分别高于同性别低年龄段儿童青少年（0.31~0.68）;坐高与下肢长比值的遗传度除9~11岁女生（0.84）外,其他年龄组均较低（男0.16~0.46,女0.21~0.57）;共同环境因素和特殊环境因素对6~14岁儿童青少年各指标的作用较大。本研究提示,在快速发育时期,坐高、下肢长和坐高与下肢长比值对环境因素更为敏感,遗传度较低;机体越成熟,其遗传效应更强。     

山东寿光汉族体质特征

在山东省寿光市调查了城市汉族306例(男为156例, 女为150例)和乡村汉族472例(男为272例, 女为200例)成人的86项体质指标, 计算了50项体质指数, 统计了指数分型情况, 对山东寿光汉族体质进行了初步分析。结果显示: (1)山东寿光汉族上眼睑皱褶率(城男为64.1%, 城女为72.0%, 乡男为79.0%, 乡女为76.5%), 山东寿光汉族蒙古褶率(城男为40.4%, 城女为60.0%, 乡男为21.0%, 乡女为34.0%), 眼裂倾斜度多为眼外角高于内角, 鼻根高度多为低型, 鼻梁侧面观多为直型, 鼻基部多上翘, 鼻孔最大径多为斜的, 鼻翼宽多为宽型, 上唇皮肤部高度多为中等型, 红唇厚度以薄唇为主, 发色多为黑色, 眼色多为褐色。城市男女肤色多为黄色, 而乡村女性肤色多为黄色, 男性多为暗黄色。(2)山东寿光汉族男女均以高头型、中鼻型、长躯干型、中肩型率最高。城市男女还以亚短腿型、宽胸型率最高, 乡村男女还以中头型(头长宽指数)、狭头型、狭面型、中骨盆型率最高。(3)山东寿光汉族男女以高身材率最高。城市男性头面部的宽度与高度, 体部的高度与宽度, 下肢、躯干与颈部的围度均高于乡村男性。城市女性骨盆宽与手足宽度比乡村女性小, 而头面部的宽度与高度, 体部的高度均高于乡村女性。(4)聚类分析显示, 山东寿光汉族体质特征与蒙古族、回族等北方族群接近。     

基诺族体质特征及35年来体质的变化

对云南西双版纳傣族自治州景洪县基诺山基诺乡的基诺族进行体质调查,测量了600例（男279人,女321人）成人人体测量学指标,与35年前在同一地区测量的基诺族体质数据进行了比较,初步分析了35年来基诺族体质变化的原因,研究表明,基诺族身材较矮,颧部不突出,上眼睑多有皱褶,接近40%成年人具有蒙古褶,眼裂高度多为中等,眼外角 多高于眼内角,鼻根高度多为中等,多为直鼻背,多直发。基诺族男性、女性均为圆头型、高头型、中头型、阔面型、中鼻型,中躯干型、中腿型、宽胸型、宽肩型、中骨盆型。这些表明基诺族具有南亚类型体质特征。35年来,基诺族男女的头长、头宽、面宽、下颌角宽、容貌面高、身高、坐高、胸围、肩宽、体重等指标值较1980年指标有所增长。基诺族体质的变化与当地生产力的发展,饮食结构的改善、体力劳动的强度变化都有一定的关系。     

Family resemblance for cranio-facial measurements in Velanti Brahmins from Andhra Pradesh, India

Maximum likelihood estimates of familial correlations are presented for 12 cranio-facial measurements taken on 399 nuclear families from Southern India. Marital resemblance is significantly different from zero for head circumference, head breadth, minimum frontal breadth, bizygomatic breadth, total facial height, and nasal height, but not for bigonial breadth, nose breadth, nose depth, or ear dimensions. All other familial correlations are significantly greater than zero except for the father-daughter correlation for nasal depth. Path analysis with a TAU transmission model with sex effects reveals that family resemblance for head circumference, head length, bigonial breadth, total facial height, and nasal height, but not for bigonial breadth, nose breadth, nose depth, or ear dimensions. All other familial correlations are significantly greater than zero except for the father-daughter correlation for nasal depth. Path analysis with a TAU transmission model with sex effects breadth, and sex effects in transmission were found for head breadth and nose dimensions. Sex effects in this sample may be due to the fact that different anthropometrists were used for male and female subjects.     

人体测量指标与掌指纹特征之间的相关研究

本文对106名中国东北汉族女性进行了活体测量,并拓取了掌指纹。样本的年龄范围为18—34岁。所分析的人体测量指标共41项,掌指纹指标共59项。将人体测量指标与掌指纹指标同时输入电子计算机,进行了100项实验指标间的相关分析,并做了相关显著性检验。在41项人体测量指标中,有35项指标与掌指纹特征有相关关系。其中与掌指纹特征同时相关的人体测量特征有18项,与指纹特征相关的人体测量指标有2项,与掌纹相关的人体测量指标有15项。与掌指纹特征同时相关的人体测量特征,与遗传因素之间的相互关系大于与指纹相关的人体测量特征。与指纹相关的人体测量特征,与遗传因素的关系,要大于与掌纹相关的人体测量特征。     

中国八甲人与空格人的体质特征

八甲人与空格人属于我国未识别族群。我们去云南省西双版纳调查了八甲人158例(男为61例,女为97例)与空格人71例(男为46例,女为25例)的86项体质指标,初步分析了八甲人与空格人的体质特征。结果如下:1)八甲人的上眼睑皱褶率男为95.08%,女为98.97%;空格人的上眼睑皱褶率男为80.43%,女为100%。八甲人蒙古褶率男为18.03%,女为29.90%;空格人的蒙古褶率男为32.61%,女为64.00%。八甲人与空格人眼裂高度多为中等,眼外角高于眼内角。八甲人男女鼻根高度多为中等。空格人男性鼻根较高,女性鼻根中等。八甲人与空格人男女均为直型鼻梁,鼻基部多为水平方向。八甲人男女颧骨体不突出。八甲人鼻翼高度约为鼻高的1/4。八甲人与空格人男女鼻翼宽与两眼内角间宽几乎等长,多为圆形耳垂,上红唇多为薄唇,唇皮类型多为中等。八甲人眼色多为褐色,空格人眼色多为黑色。2)根据头面部、体部指数分型,八甲人与空格人男女均以高头型率、阔头型率、中鼻型率、中腿型率、宽肩型率、身材矮型率最高。八甲人男女还以圆头型率、长躯干型率、宽胸型率最高。空格人男女还以中胸型率、窄骨盆型率最高。八甲人与空格人男性还以阔面型率最高,而女性则以中面型率最高。3)聚类分析显示八甲人与空格人体质特征属于南方族群类型。     

Measurement and study of the nose and face and their correlations in the young adult of Han nationality

The measurement of 13 items in the face and nose of 220 young adults (110 males and 110 females) of the Han nationality between the ages of 18 and 21 years has been done in the Henan Province of China. The means and standard deviations have been obtained, and the significant differences in many items between males and females have been proved. Some items influencing outer nasal shape have been analyzed. The correlations between nose height, nose length, and morphologic facial height and physiognomic facial height have been discussed. The ratio and amount of nasal breadth to facial breadth and nasal breadth to interocular breadth have been compared and analyzed, and the differences among the different races and between the sexes have been explained.     

Physical characteristics of Chinese Hakka

Using standard and internationally validated methods,86 anthropologic characteristics were determined in 650 male(305 from urban areas and 345 from rural areas) and 704 female(331 from urban areas,373 from rural areas) Chinese Hakka adults living in Guangdong and Jiangxi.The data were used to calculate 24 anthropologic indices,which were analyzed statistically.The physical characteristics of Hakka subjects were analyzed and compared with reference ethnic data.There were four main findings of this study.First,a small proportion of Hakka adults had an eye fold on the upper eyelid,but a large proportion had a mongoloid fold.The eye slits were narrow in most adults,had a medium nasal root height and straight bridges,and most of the external angles were prominent.The nasal base was upturned in most men.The distributions of the three types of nasal base in women were similar.The proportions of subjects with middle and high alae nasi heights were high and similar.Males with a maximum nostril diameter were mostly classified as transverse and oblique,while many women were classified as transverse and had relatively wide alae nasi.The round lobe type was the most common.Upper lip skin height was mostly classified as medium.Lips were classified as thin.The hair was black,eyes were brown,and the skin was yellowish.Second,the head length was long in male Hakka.The minimum frontal breadth,face breadth,lip height,and interocular breadth were similar to those of North-Asian populations.Meanwhile,head breadth,morphological facial height,nose breadth,mouth breadth,and nose height were similar to those of South-Asian populations.Head length was long in female Hakka.The minimum frontal breadth,face breadth,lip height,and interocular breadth were similar to those of North-Asian populations.Head breadth,nose breadth,and mouth breadth were similar to those of South-Asian populations.Third,the stature of male and female Hakka in urban and rural areas was classified as medium.The proportions of male and female Hakka classified as mesocephaly(length-breadth index of the head),hypsicephalic type,metriocephalic type(breadth-height index of the head) mesorrhiny,long trunk,subbrachyskelic type,broad shoulder breadth,and narrow distance between iliac crests were higher than those of other types.Finally,principal component analyses showed that the physical characteristics of Hakka were between those of South-Asian and North-Asian ethnic populations,but were generally closer to those of North-Asian populations in China.     

孟高棉语族未识别民族的体质特征

为了探究孟高棉语族未识别民族族群特征,研究组以412名（男性220人,女性192人）云南孟高棉语族未识别民族成人为例,运用人体测量学方法对该族群男女头面部与体部58项指标及20个指数进行测量和分析,并选取头长、头宽、面宽、形态面高、身高、坐高、肩宽、骨盆宽8项指标与30个已研究族群进行比较。结果表明：1)男性各项体质指标除大腿围和6项皮褶厚度指标外,都大于女性各项指标,男女身高均以矮型为主;2）孟高棉语族未识别民族男性上眼睑皱褶率为88.2%,女性上眼睑皱褶率为94.3%。男性蒙古褶率为41.8%,女性蒙古褶率为36.5%。鼻根高度男性以中等型为主,女性以低平为主。耳垂类型男性以圆形率为主,女性以三角形率为主;3）依据指数分型出现率得出：孟高棉语族未识别民族男女均以圆头型、高头型、阔头型、狭鼻型、中腿型、中胸型、宽肩型率最高;4）聚类分析和主成分分析显示孟高棉语族未识别民族与布朗族、基诺族、布依族、侗族比较接近。遗传因素、环境条件与饮食习惯是这些民族体质特征接近的原因。     

Craniofacial variation and growth in the Prader-Labhart-Willi syndrome

A study of anthropometric variation and craniofacial growth in individuals with the Prader-Labhart-Willi syndrome (PLWS) illustrates the utility of anthropometry in clinical evaluation and research. Anthropometric measurements, including head length and breadth, minimum frontal diameter, and head circumference, were obtained on 38 PLWS individuals (21 with chromosome 15 deletions) with an age range from 2 weeks to 39 years. No anthropometric differences were found between the two chromosome subgroups. A relative deceleration in the growth of certain craniofacial dimensions (head circumference and length) is suggested by the negative correlations between age and Z-scores for the measurements. Raw values for minimum frontal diameter and head breadth were near or below the 5th percentile curve, while almost all values for head length and circumference fell within normal limits. The data support suggestions that dolichocephaly be considered an early diagnostic feature of PLWS. Furthermore, the status of narrow bifrontal diameter as a major feature of PLWS is confirmed.