共查询到20条相似文献,搜索用时 441 毫秒
1.
Isidoro González-Alvaro Miguel Angel Descalzo Loreto Carmona the EMECAR Study Group 《Arthritis research & therapy》2008,10(6):R138
Introduction
The disease activity in patients with rheumatoid arthritis has improved during the past decade. The availability of new drugs and also a better assessment of the disease have been proposed to be responsible for this improvement. In the present work we estimate the effect of these factors on disease activity and function in patients with rheumatoid arthritis at the beginning of the new century. 相似文献2.
Jacques-Eric Gottenberg Corinne Miceli-Richard Béatrice Ducot Philippe Goupille Bernard Combe Xavier Mariette 《Arthritis research & therapy》2009,11(4):R114-8
Introduction
Little is known about systemic B-cell activation in early rheumatoid arthritis (RA). We therefore evaluated the serum levels of markers of B-cell activation in patients included in the ESPOIR early arthritis cohort. 相似文献3.
Lotte A van de Stadt Wouter H Bos Marlies Meursinge Reynders Helen Wieringa Franktien Turkstra Conny J van der Laken Dirkjan van Schaardenburg 《Arthritis research & therapy》2010,12(3):R98
Introduction
Ultrasonography (US) has better sensitivity than clinical evaluation for the detection of synovitis in early rheumatoid arthritis (RA). Patients presenting with arthralgia and a positive anti-citrullinated protein antibodies (ACPA) and/or Rheumatoid Factor (IgM-RF) status are at risk for developing RA. In the present study, US utility and predictive properties in arthralgia patients at risk for the development of arthritis were studied. 相似文献4.
Ravi C Dwivedi Navjot Dhindsa Oleg V Krokhin John Cortens John A Wilkins Hani S El-Gabalawy 《Arthritis research & therapy》2009,11(2):R32-11
Introduction
Although the clinical effects of infliximab therapy in rheumatoid arthritis have been documented extensively, the biological effects of this intervention continue to be defined. We sought to examine the impact of infliximab therapy on the serum proteome of rheumatoid arthritis patients by means of a mass spectrometry-based approach. 相似文献5.
Alejandro Balsa Arancha Cabezón Gisela Orozco Tatiana Cobo Eugenia Miranda-Carus Miguel Ángel López-Nevot José Luis Vicario Emilio Martín-Mola Javier Martín Dora Pascual-Salcedo 《Arthritis research & therapy》2010,12(2):R62
Introduction
The purpose of this study was to investigate the association between HLA-DRB1 alleles with susceptibility to rheumatoid arthritis (RA) and production of antibodies against citrullinated proteins (ACPA) and rheumatoid factor (RF). 相似文献6.
Maria D Mjaavatten Till Uhlig Anne J Haugen Halvor Nygaard Göran Sidenvall Knut Helgetveit Tore K Kvien 《Arthritis research & therapy》2009,11(5):R146-8
Introduction
The current 1987 American College of Rheumatology (ACR) classification criteria for rheumatoid arthritis (RA) have proven less useful in early arthritis. The objective of this study was to identify and compare predictors of three relevant outcomes of chronic arthritis in a cohort of very early arthritis patients. 相似文献7.
Vincent Goëb Marlène Thomas-L'Otellier Romain Daveau Roland Charlionet Patrice Fardellone Xavier Le Loët François Tron Danièle Gilbert Olivier Vittecoq 《Arthritis research & therapy》2009,11(2):R38-14
Introduction
The aim of our study was to identify new early rheumatoid arthritis (RA) autoantibodies. 相似文献8.
Madsen RK Lundstedt T Gabrielsson J Sennbro CJ Alenius GM Moritz T Rantapää-Dahlqvist S Trygg J 《Arthritis research & therapy》2011,13(1):R19
Introduction
The aim of this study was to assess the feasibility of diagnosing early rheumatoid arthritis (RA) by measuring selected metabolic biomarkers. 相似文献9.
Introduction
The objective was to study immune regulation in a mouse model of rheumatoid arthritis that exhibits considerable heterogeneity of disease activity. 相似文献10.
Liesu Meng Wenhua Zhu Congshan Jiang Xiaojing He Weikun Hou Fang Zheng Rikard Holmdahl Shemin Lu 《Arthritis research & therapy》2010,12(3):R103
Introduction
Toll-like receptors (TLRs) are involved in both innate and adaptive immune responses and are likely to play a complex role in the pathogenesis of human rheumatoid arthritis (RA) and experimental arthritis. The objective of this study was to identify the key TLR in pristane-induced arthritis (PIA), a rat model for RA, and to clarify its roles in the initiation and maintenance of arthritis. 相似文献11.
Sofia S Lindblad Piotr Mydel Ing-Marie Jonsson Robert M Senior Andrej Tarkowski Maria Bokarewa 《Arthritis research & therapy》2009,11(3):R88
Introduction
Recent epidemiologic studies have implicated smoking as an environmental risk factor for the development of rheumatoid arthritis (RA). The aim of the present study is the evaluation of the role of cigarette smoke (CS) in the pathogenesis of collagen-induced arthritis in mice. 相似文献12.
A rational use of glucocorticoids in patients with early arthritis has a minimal impact on bone mass
Monica Ibañez Ana M Ortiz Isabel Castrejón J Alberto García-Vadillo Inmaculada Carvajal Santos Castañeda Isidoro González-Álvaro 《Arthritis research & therapy》2010,12(2):R50
Introduction
Glucocorticoid (GC)-induced osteoporosis is a frequent complication in patients with rheumatoid arthritis. However, little information exists about the consequences of GC use in patients with early arthritis. Here we describe the variables underlying the use of GC in early arthritis, as well as its effect on bone-mineral density. 相似文献13.
14.
Andrés Cerezo L Mann H Pecha O Pleštilová L Pavelka K Vencovský J Senolt L 《Arthritis research & therapy》2011,13(4):R122
Introduction
The aim of this study was to examine the serum levels of S100 proteins and to evaluate their role in patients with recent-onset rheumatoid arthritis (RA). 相似文献15.
Bianca Miterski Susanne Drynda Gundula B?schow Wolfram Klein Joachim Oppermann J?rn Kekow J?rg Thomas Epplen 《BMC genetics》2004,5(1):2
Background
Rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) are complex multifactorial diseases caused by environmental influences and an unknown number of predisposing genes. The present study was undertaken in order to investigate association of polymorphisms in candidate genes with RA and JRA in German subjects. 相似文献16.
Kim SY Servi A Polinski JM Mogun H Weinblatt ME Katz JN Solomon DH 《Arthritis research & therapy》2011,13(1):R32
Introduction
Health care utilization databases have been increasingly used for studies of rheumatoid arthritis (RA). However, the accuracy of RA diagnoses in these data has been inconsistent. 相似文献17.
Jeffrey H Ruth Christy C Park M Asif Amin Charles Lesch Hubert Marotte Shiva Shahrara Alisa E Koch 《Arthritis research & therapy》2010,12(3):R118
Introduction
The function of interleukin-18 (IL-18) was investigated in pertinent animal models of rodent rheumatoid arthritis (RA) to determine its proinflammatory and monocyte recruitment properties. 相似文献18.
Hyun-Mi Choi Yeon-Ah Lee Sang-Hoon Lee Seung-Jae Hong Dae-Hyun Hahm Sang-Yun Choi Hyung-In Yang Myung Chul Yoo Kyoung Soo Kim 《Arthritis research & therapy》2009,11(6):R161-10
Introduction
The role of adiponectin in the pathogenesis of arthritis is still controversial. This study was performed to examine whether adiponectin is involved in joint inflammation and destruction in rheumatoid arthritis (RA) in relation to the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs). 相似文献19.
Zhao X Okeke NL Sharpe O Batliwalla FM Lee AT Ho PP Tomooka BH Gregersen PK Robinson WH 《Arthritis research & therapy》2008,10(4):R94
Introduction
There is increasing evidence that autoantibodies and immune complexes (ICs) contribute to synovitis in rheumatoid arthritis (RA), yet the autoantigens incorporated in ICs in RA remain incompletely characterised. 相似文献20.
Gabor Er?s Saleh Ibrahim Nikolai Siebert Mihály Boros Brigitte Vollmar 《Arthritis research & therapy》2009,11(2):R43