Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily

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Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition

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Accurate de novo design of membrane-traversing macrocycles

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helixCAM: A platform for programmable cellular assembly in bacteria and human cells

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Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants

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Disease-linked mutations cause exposure of a protein quality control degron

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Structure and engineering of the minimal type VI CRISPR-Cas13bt3

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Mutational fitness landscape of human influenza H3N2 neuraminidase

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Co-crystallization with diabodies: A case study for the introduction of synthetic symmetry

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Structure-guided optimization of light-activated chimeric G-protein-coupled receptors

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Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome

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IPRO+/−: Computational Protein Design Tool Allowing for Insertions and Deletions

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DStabilize: A Web Resource to Generate Mirror Images of Biomolecules

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Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity

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Most non-canonical proteins uniquely populate the proteome or immunopeptidome

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Redesigning HVEM Interface for Selective Binding to LIGHT,BTLA, and CD160

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Deterministic and Stochastic Rules of Branching Govern Dendrite Morphogenesis of Sensory Neurons

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Deamidation of the human eye lens protein γS-crystallin accelerates oxidative aging

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The RNA-Binding Protein Rasputin/G3BP Enhances the Stability and Translation of Its Target mRNAs

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Phage-assisted evolution and protein engineering yield compact,efficient prime editors

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