Honey bees are among the most important pollinators in agriculture. Pyrethroids are an important class of broad-spectrum insecticides that are often highly toxic to pollinators such as honey bees. This article summarizes the mode of action of pyrethroids to insects. Reports of pyrethroid residues in colonies and hive products, the acute toxicity of these compounds to honey bees, and their sublethal effects are reviewed. The effects of mixed-pesticide formulations containing pyrethroids on honey bees are discussed. Therefore, to ensure the safe of honey bee pollination, strengthening the comprehensive and green means of pest control, replacing chemical pesticides with environment-friendly biological pesticides, and using reasonably and scientifically are necessary; accelerating the research and development of insecticides with high efficiency to target pests and those with highly selective to pests but low or non toxic to honey bees are needed too .