New Eudesmane Sesquiterpenoids from Salvia plebeia R. Br. |
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| Authors: | Lie‐Feng Ma Peng‐Fei Wang Ji‐Dong Wang Xiang‐Min Tong Wei‐Guang Shan Hui Zhang Zha‐Jun Zhan |
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| Institution: | 1. College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China;2. Department of New Drug Screening, Zhejiang Hisun Pharmaceutical Co., Ltd., Taizhou, P. R. China;3. Clinical Research Institute, Zhejiang Provincial People's Hospital, Hangzhou, P. R. China |
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| Abstract: | Three new sesquiterpenoids, salplebeones A – C ( 1 – 3 ), were isolated from the ethanol‐soluble extract of the aerial part of Salvia plebeia R. Br . Their structures were established by detailed analysis of NMR and MS spectra. Salplebeone A was an eudesmane lactone, while salplebeones B and C were rare eudesmane sesquiterpenoids, containing 12,8‐lactam groups. Antiproliferative activities of salplebeones A – C to myeloid leukemia cell lines were evaluated. |
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| Keywords: | Salvia plebeia R Br Eudesmane Sesquiterpenoids Salplebeone |
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