New monoclonal antibodies to the Ebola virus glycoprotein: Identification and analysis of the amino acid sequence of the variable domains |
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| Authors: | A A Panina T K Aliev O B Shemchukova I G Dement’yeva N E Varlamov L P Pozdnyakova M N Bokov D A Dolgikh P G Sveshnikov M P Kirpichnikov |
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| Abstract: | We determined the nucleotide and amino acid sequences of variable domains of three new monoclonal antibodies to the glycoprotein of Ebola virus capsid. The framework and hypervariable regions of immunoglobulin heavy and light chains were identified. The primary structures were confirmed using massspectrometry analysis. Immunoglobulin database search showed the uniqueness of the sequences obtained. |
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