Mutation in the <Emphasis Type="Italic">Drosophila</Emphasis> insulin-like receptor substrate, <Emphasis Type="Italic">chico</Emphasis>, affects the neuroendocrine stress-reaction development

It is shown for the first time that the insulin receptor substrate gene chico controls the functioning of the systems of metabolism of dopamine and juvenile hormone in Drosophila melanogaster females under normal conditions and in thermal stress.