Secretory carrier membrane proteins |
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Authors: | Angus Ho Yin Law Cheung-Ming Chow Liwen Jiang |
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Institution: | (1) School of Life Sciences, Centre for Cell and Developmental Biology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; |
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Abstract: | Secretory carrier membrane proteins (SCAMPs) are a family of integral membrane proteins that play roles in mediating exocytosis
in animal cells. However, relatively little is known about the subcellular localization, trafficking, and function of SCAMPs
in plants. Several recent studies in plant cells indicate that plant SCAMPs share many similarities with their mammalian homologs
although there are differences. In this review, we will first summarize and compare animal and plant SCAMPs in terms of their
subcellular localization, trafficking, and possible functions. We will then present a phylogenetic analysis of plant and animal
SCAMPs. Finally, we will present expression analysis on selective Arabidopsis SCAMPs in the hope of pointing to directions for functional characterization of plant SCAMPs in the future. |
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