| Abstract: | Reactions of neurons of area 7 in the parietal association cortex to paired stimulation of the dorsolateral and posteriolateral thalamic nuclei were investigated using methods of extra- and intracellular recording. It was found that conditioning stimulation of association nuclei caused inhibition or facilitation of the test response; in some cases, the effect was indeterminant. Inhibition frequently led to other types of reactions. Inhibition of response to the test stimulus was pronounced during the initial period of IPSP, but facilitation of the response was possible during the repolarization phase. There was no inhibition of test responses when the chloride component of the IPSP was reversed. It is suggested that inhibition of responses to the test stimulus takes place in the presence of an inward chloride current and that facilitation of responses to such a stimulus may be due to increased effectiveness of late EPSPS.I. I. Mechnikov State University, Odessa. Translated from Neurofiziologiya, Vol. 24, No. 2, pp. 198–207, March–April, 1992. |
