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MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data |
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| Authors: | Scott W Doniger Nathan Salomonis Kam D Dahlquist Karen Vranizan Steven C Lawlor Bruce R Conklin |
| Affiliation: | 1. Gladstone Institute of Cardiovascular Disease, University of California, 94141-9100, San Francisco, CA, USA 2. Cardiovascular Research Institute, University of California, 94143, San Francisco, CA, USA 4. Functional Genomics Lab, University of California, 94720, Berkeley, CA, USA 3. Departments of Medicine and Cellular and Molecular Pharmacology, University of California, 94143, San Francisco, CA, USA |
| Abstract: | MAPPFinder is a tool that creates a global gene-expression profile across all areas of biology by integrating the annotations of the Gene Ontology (GO) Project with the free software package GenMAPP http://www.GenMAPP.org. The results are displayed in a searchable browser, allowing the user to rapidly identify GO terms with over-represented numbers of gene-expression changes. Clicking on GO terms generates GenMAPP graphical files where gene relationships can be explored, annotated, and files can be freely exchanged. |
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