Catalase as a source of both X- and V-factor for Haemophilus influenzae |
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Authors: | Morton Daniel J VanWagoner Timothy M Seale Thomas W Whitby Paul W Stull Terrence L |
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Institution: | Department of Pediatrics, University of Oklahoma Health Sciences Center, 940 NE 13th Street, Oklahoma City, OK 73104, USA. |
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Abstract: | Haemophilus influenzae requires two growth factors, designated factor X (porphyrin) and factor V (NAD). Mammalian catalases contain both bound heme and NADPH. This study shows that catalase can supply both factors X and V to H. influenzae in vitro, thus representing a potential in vivo source of these essential growth factors. |
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Keywords: | Haemophilus influenzae catalase heme NAD |
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