Variations of hepatic dolichols during rat development |
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| Authors: | M Marino A M Girelli S Leoni A Trentalance |
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| Affiliation: | Dipartimento di Biologia Cellulare e dello Sviluppo, Universita' La Sapienza, Roma, Italy. |
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| Abstract: | The content and the percent distribution of dolichol and dolichyl phosphate homologues were measured by high-performance liquid chromatography in perinatal rat livers. Short dolichol chains and no dolichyl phosphate are detectable in the liver at foetal stages; dolichol content progressively increases during liver development. A good correlation is observable between the changes of the dolichol, dolichyl phosphate and the activity of dolichyl-phosphate phosphatase. |
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