Establishment of a persistent mutant of canine distemper virus |
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| Authors: | Iwatsuki K Ikeda Y Ohashi K Nakamura K Kai C |
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| Institution: | Department of Veterinary Microbiology, Graduate School of Agricultural and Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. |
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| Abstract: | We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established. |
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