Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA;2. Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA;3. Department of Spine Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China;4. Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China