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Polymorphism in regulatory gene sequences
Authors:N A Mitchison
Affiliation:Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK. n.mitchison@ucl.ac.uk
Abstract:The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies.
Keywords:
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