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Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax
Affiliation:1. The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia;2. University of Melbourne, Melbourne, 3010 VIC, Australia;3. Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA
Abstract:
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  • Keywords:malaria  aspartic protease  antimalarial  plasmepsin IX  plasmepsin X  protein-drug structure  enzzyme kinetics
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