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Redox-dependent structure and dynamics of macrophage migration inhibitory factor reveal sites of latent allostery
Affiliation:1. Department of Molecular Biology, Cell Biology, & Biochemistry, Brown University, Providence, RI 02903, USA;2. Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA;3. Section of Neonatology, Department of Pediatrics, Cooper University Hospital, Camden, NJ 08103, USA;4. Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA;5. Department of Biochemistry and Biophysics and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Abstract:
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  • Keywords:cytokine  allostery  NMR  redox  MIF
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