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Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability
Institution:1. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA;2. Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA;3. Electron Microscopy Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA
Abstract:
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  • Keywords:beta-coronavirus  broadly neutralizing antibody  COVID-19  crystal structure  SARS-CoV-2  S2-directed antibody  vaccine design
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