Fermentative production of l-lactic acid by Lactobacillus casei DSM 20011 and product recovery using ion exchange resins |
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| Authors: | Giuseppe Vaccari Antonio R. y González-Vara Anna L. Campi Elisabetta Dosi Patrizia Brigidi Diego Matteuzzi |
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| Affiliation: | (1) Department of Chemistry, University of Ferrara, via Borsari 46, 44100 Ferrara, Italy;(2) Department of Pharmaceutical Sciences, Interdepartmental Center for Biotechnology, University of Bologna, via Belmeloro 6, 40126 Bologna, Italy;(3) Institute of Pharmaceutical and Toxicological Chemistry, University of Catania, Catania, Italy |
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| Abstract: | In order to produce l(+)-lactic acid to be employed in poly-l-lactic acid polymer production, for biomedical applications, the strain Lactobacillus casei subsp. casei DSM 20011 was studied in a conventional batch mode using different initial concentrations of glucose. The results obtained showed that the initial glucose concentration exerts an influence on the fermentation pattern, modifying the different fermentation parameters. Nevertheless, the product yield remained at a constant value of 0.86 g·g–1. The proposed novel system of product recovery, based on the use of ion-exchange resins, gave high yields of pure lactic acid.Correspondence to: D. Matteuzzi |
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