Apelin and its g protein-coupled receptor regulate cardiac development as well as cardiac function |
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Authors: | Quertermous Thomas |
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Institution: | Division of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA. tomq1@stanford.edu |
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Abstract: | The Apelin pathway has only recently emerged as an important regulator of cardiac and vascular function, mediating adaptation to physiological stress and disease. In this issue of Developmental Cell, experiments in zebrafish convincingly show a critical role for this pathway in myocardial cell specification and heart development. |
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