Morphology and growth rate changes in Chinese hamster cells cultured in presence of sodium butyrate |
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| Authors: | J A Wright |
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| Institution: | Department of Microbiology, The University of Manitoba, Winnipeg, Manitoba, Canada |
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| Abstract: | Chinese hamster ovary cells cultured in the presence of sodium butyrate decrease their growth rate, increase in length, and tend to grow in a monolayer. The addition of the same concentrations of sodium isobutyrate are completely ineffective. The growth alterations produced by 5 × 10−4 M sodium butyrate are similar to those caused by dibutyryl adenosine 3′:5′-cyclic monophosphate treatment. |
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