Supersensitive double mutants in yeast |
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Authors: | N. A. Khan M. Brendel R. H. Haynes |
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Affiliation: | (1) Department of Biology, York University, Toronto, Canada |
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Abstract: | Summary Double mutants containing the radiosensitive alleles uxsl (UVR-EXR-) and either uvsl-2 or uvsl 9-2 (both UVR-EXR+) have been constructed. We find that these double mutants are extremely sensitive to UV: their LD37 doses are 0.3–0.5 ergs/mm2 as compared to 16–40 ergs/mm2 for the radiosensitive parental strains carrying only a single mutant gene and 456 ergs/mm2 for wild-type. |
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