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Carbohydrate-mediated Recognition of Larval Mosquito Hosts by Romanomermis culicivorax
Authors:James L Kerwin  Kathi A Zurakowski  Robert K Washino
Abstract:Proteases, glycosidases, and lectins were tested and the results supported a role in host recognition for glycoproteins containing β-glucose and α-mannose on the cuticular surface of host and parasite. Carbohydrates containing α-glucose, galactose, fucose, or N-acetylglucosamine residues apparently are not involved in nematode attachment. Chitin or a related N-acetylglucosamine polymer was found in R. culicivorax preparasites. Treatment of preparasites with neuraminidase, which hydrolyzes sialic acids, increased nematode attachment to Anopheles freeborni larvae.
Keywords:Anopheles freeborni  carbohydrate  host recognition  mosquito cuticle  nematode cuticle  Romanomermis culicivorax
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