Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid |
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| Authors: | Su Fei Yu Bo Sun Jibin Ou Hong-Yu Zhao Bo Wang Limin Qin Jiayang Tang Hongzhi Tao Fei Jarek Michael Scharfe Maren Ma Cuiqing Ma Yanhe Xu Ping |
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| Affiliation: | State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China. |
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| Abstract: | Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid. |
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