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Iridoid glucosides from roots of Vietnamese Paederia scandens
Authors:Quang Dang Ngoc  Hashimoto Toshihiro  Tanaka Masami  Dung Nguyen Xuan  Asakawa Yoshinori
Affiliation:Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Abstract:Four iridoid glucosides, three of which are dimeric were isolated from the methanol extract of roots of Vietnamese Paederia scandens (Lour) Merrill together with the five known glucosides, paederoside, asperuloside, paederosidic acid, asperulosidic acid and geniposide. Seven sulfur-containing iridoid glucosides were also isolated. The structures of the iridoid glucosides were determined by a combination of high-resolution NMR, MS, IR and UV spectra, and chemical reaction such as acetylation.
Keywords:Paederia scandens   Rubiaceae   Paederoside   Paederosidic acid   Asperuloside   Asperulosidic acid   Geniposide   Paederosidic acid methyl ester   Dimeric iridoid glucoside
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