Asymmetric expression of antivin/lefty1 in the early chick embryo |
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| Authors: | Ishimaru Y Yoshioka H Tao H Thisse B Thisse C V E Wright C Hamada H Ohuchi H Noji S |
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| Institution: | Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima, 2-1 Minami-Jyosanjima-cho, Tokushima, Japan. |
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| Abstract: | Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo. |
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