Predicting protein-protein binding sites in membrane proteins |
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Authors: | Andrew J Bordner |
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Affiliation: | (1) Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA |
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Abstract: | Background Many integral membrane proteins, like their non-membrane counterparts, form either transient or permanent multi-subunit complexes in order to carry out their biochemical function. Computational methods that provide structural details of these interactions are needed since, despite their importance, relatively few structures of membrane protein complexes are available. |
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