Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene |
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| Authors: | Petra Kempna Roberta Ricciarelli Angelo Azzi Jean-Marc Zingg |
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| Institution: | 1.Department of Pediatric Endocrinology and Diabetology,University Children’s Hospital,Bern,Switzerland;2.Department of Experimental Medicine,University of Genoa,Genoa,Italy;3.Institute of Biochemistry and Molecular Medicine,Universit?t Bern University of Bern,Bern,Switzerland;4.Vascular Biology Laboratory, Office 621, JM USDA-Human Nutr. Res. Ctr. On Aging,Tufts University,Boston,USA |
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| Abstract: | Three closely related human SEC14p-like proteins (hTAP1, hTAP2, hTAP3, or SEC14L2, SEC14L3, SEC14L4, respectively) have been
described that are related to the Saccharomyces cerevisiae SEC14 protein. These proteins may participate in intracellular lipid transport and influence regulatory lipid-dependent events.
Here we report the isolation of an alternatively spliced hTAP3 cDNA and a polymorphism within the coding region of the hTAP3/SEC14L4
gene. |
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